CAS 108929-11-9: 1,N(2)-ethenodeoxyguanosine

Description:1,N(2)-Ethenodeoxyguanosine is a modified nucleoside that arises from the reaction of deoxyguanosine with certain electrophiles, particularly in the context of DNA damage caused by environmental factors such as alkylating agents or oxidative stress. This compound features an etheno group at the N(2) position of the guanine base, which can lead to mispairing during DNA replication, potentially resulting in mutations. The presence of the etheno modification can affect the stability and structure of DNA, influencing its interactions with enzymes and other biomolecules. As a result, 1,N(2)-ethenodeoxyguanosine is often studied in the context of mutagenesis and carcinogenesis. Its detection and quantification in biological samples can provide insights into the extent of DNA damage and the cellular response to genotoxic stress. The compound is also of interest in the field of cancer research, as understanding its formation and repair mechanisms may contribute to the development of therapeutic strategies targeting DNA damage.

Formula:C₁₂H₁₃N₅O₄

InChI:InChI=1/C12H13N5O4/c18-4-7-6(19)3-8(21-7)17-5-14-9-10(17)15-12-13-1-2-16(12)11(9)20/h1-2,5-8,18-19H,3-4H2,(H,13,15)/t6-,7+,8-/m0/s1

Synonyms:
1,N(2)-Edguo
9H-Imidazo(1,2-a)purin-9-one, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4-dihydro-
3-(2-deoxy-alpha-D-erythro-pentofuranosyl)-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one

Found 3 products.

Product data	Purity	Price range	Estimated delivery
1, N2-Etheno-2'-deoxyguanosine-13C5 REF: TR-E677903CAS: 108929-11-9	- - -	1,201.00 €~4,238.00 €	Mon 21 Apr 25
1, N2-Etheno-2-deoxyguanosine REF: 3D-IEA92911CAS: 108929-11-9	Min. 95%	380.00 €~2,474.00 €	Tue 22 Apr 25
1, N2-Etheno-2’-deoxyguanosine REF: TR-E677895CAS: 108929-11-9	- - -	- - -	Discontinued product