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CAS 108929-11-9

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1,N(2)-ethenodeoxyguanosine

Description:
1,N(2)-Ethenodeoxyguanosine is a modified nucleoside that arises from the reaction of deoxyguanosine with certain electrophiles, particularly in the context of DNA damage caused by environmental factors such as alkylating agents or oxidative stress. This compound features an etheno group at the N(2) position of the guanine base, which can lead to mispairing during DNA replication, potentially resulting in mutations. The presence of the etheno modification can affect the stability and structure of DNA, influencing its interactions with enzymes and other biomolecules. As a result, 1,N(2)-ethenodeoxyguanosine is often studied in the context of mutagenesis and carcinogenesis. Its detection and quantification in biological samples can provide insights into the extent of DNA damage and the cellular response to genotoxic stress. The compound is also of interest in the field of cancer research, as understanding its formation and repair mechanisms may contribute to the development of therapeutic strategies targeting DNA damage.
Formula:C12H13N5O4
InChI:InChI=1/C12H13N5O4/c18-4-7-6(19)3-8(21-7)17-5-14-9-10(17)15-12-13-1-2-16(12)11(9)20/h1-2,5-8,18-19H,3-4H2,(H,13,15)/t6-,7+,8-/m0/s1
Synonyms:
  • 1,N(2)-Edguo
  • 9H-Imidazo(1,2-a)purin-9-one, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)-3,4-dihydro-
  • 3-(2-deoxy-alpha-D-erythro-pentofuranosyl)-3,4-dihydro-9H-imidazo[1,2-a]purin-9-one
  • 1,N(2)-Ethenodeoxyguanosine
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Found 2 products.
  • 1, N2-Etheno-2'-deoxyguanosine-13C5
    TRC
    + Info

    1, N2-Etheno-2'-deoxyguanosine-13C5

    Controlled Product
    CAS:
    <p>Applications 1, N2-Etheno-2’-deoxyguanosine-13C5 is caused by exposure to pollutants. It is an isotopically labeled analog of the 2’-Deoxyguanosine adduct.<br></p>
    Formula:C713C5H13N5O4
    Color and Shape:Neat
    Molecular weight:296.23

    Ref: TR-E677903

    1mg
    1,624.00€
    500µg
    1,065.00€
    2500µg
    3,760.00€
  • 1, N2-Etheno-2-deoxyguanosine
    Biosynth
    + Info

    1, N2-Etheno-2-deoxyguanosine

    CAS:
    <p>Please enquire for more information about 1, N2-Etheno-2-deoxyguanosine including the price, delivery time and more detailed product information at the technical inquiry form on this page</p>
    Formula:C12H13N5O4
    Purity:Min. 95%
    Molecular weight:291.26 g/mol

    Ref: 3D-IEA92911

    5mg
    191.00€
    10mg
    255.00€