Suc-Ala-Ala-Pro-Lys-pNA, also known as Succinyl-Ala-Ala-Pro-Lys-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays to study proteolytic enzymes, particularly serine proteases. This compound features a sequence of amino acids, including alanine, proline, and lysine, with a succinyl group at the N-terminus and a p-nitroanilide moiety at the C-terminus, which serves as a chromogenic indicator. Upon cleavage by specific proteases, the release of p-nitroaniline results in a measurable color change, allowing for quantification of enzyme activity. The peptide's structure contributes to its specificity and reactivity, making it a valuable tool in enzymology and related fields. Additionally, its solubility in aqueous solutions and stability under physiological conditions enhance its utility in laboratory settings. Overall, Suc-Ala-Ala-Pro-Lys-pNA is an important reagent for studying enzyme kinetics and mechanisms in various biological research applications.

Suc-Ala-Ala-Pro-Lys-pNA

108929-39-1: Suc-Ala-Ala-Pro-Lys-pNA, also known as Succinyl-Ala-Ala-Pro-Lys-p-nitroanilide, is a synthetic peptide substrate commonly used in biochemical assays to study proteolytic enzymes, particularly serine proteases. This compound features a sequence of amino acids, including alanine, proline, and lysine, with a succinyl group at the N-terminus and a p-nitroanilide moiety at the C-terminus, which serves as a chromogenic indicator. Upon cleavage by specific proteases, the release of p-nitroaniline results in a measurable color change, allowing for quantification of enzyme activity. The peptide's structure contributes to its specificity and reactivity, making it a valuable tool in enzymology and related fields. Additionally, its solubility in aqueous solutions and stability under physiological conditions enhance its utility in laboratory settings. Overall, Suc-Ala-Ala-Pro-Lys-pNA is an important reagent for studying enzyme kinetics and mechanisms in various biological research applications.

Suc-AAPK-pNA, a substrate for wild-type and K188D/D189K trypsins (Km = 105 mM respectively 651 mM).

<p>Suc-Ala-Ala-Pro-Lys-pNA is a hybrid peptide that was expressed and purified from the gene product of the human serine protease, pancreatic elastase. It has been shown to have high salt and pH stability and predominately exists as a single polypeptide chain. Suc-Ala-Ala-Pro-Lys-pNA has been shown to enhance the immunofluorescence of inflammatory cells in vitro, suggesting it may be used as a therapeutic agent for inflammatory diseases. In addition, this hybrid peptide has also demonstrated protease activity.</p>

CAS 108929-39-1

Suc-Ala-Ala-Pro-Lys-pNA

Suc-Ala-Ala-Pro-Lys-pNA

Ref: 01-4017329

Suc-Ala-Ala-Pro-Lys-pNA

Ref: 3D-FS110776