CAS 108964-32-5

Fura 2AM

Description:

Fura 2AM is a cell-permeable fluorescent calcium indicator commonly used in biological research to measure intracellular calcium levels. It is a derivative of the Fura-2 dye, designed to enter cells easily due to the acetoxymethyl (AM) ester groups, which are hydrolyzed by intracellular esterases to release the active form. Fura 2AM exhibits a characteristic fluorescence that changes in response to calcium ion concentration, allowing researchers to monitor dynamic changes in calcium levels in real-time. The excitation and emission properties of Fura 2AM enable it to be used in fluorescence microscopy and flow cytometry. Its ability to provide quantitative measurements of calcium fluctuations makes it valuable in studies related to cell signaling, muscle contraction, and neurotransmitter release. Additionally, Fura 2AM is often utilized in combination with other fluorescent probes to study complex cellular processes. However, proper controls and calibration are essential for accurate interpretation of the data obtained using this indicator.

Formula: C₄₄H₄₇N₃O₂₄

InChI: InChI=1S/C44H47N3O24/c1-25-7-8-32(46(16-39(53)65-20-60-26(2)48)17-40(54)66-21-61-27(3)49)35(11-25)58-9-10-59-36-12-31-13-37(43-45-15-38(71-43)44(57)69-24-64-30(6)52)70-34(31)14-33(36)47(18-41(55)67-22-62-28(4)50)19-42(56)68-23-63-29(5)51/h7-8,11-15H,9-10,16-24H2,1-6H3

InChI key: InChIKey=VPSRLGDRGCKUTK-UHFFFAOYSA-N

SMILES: N(CC(OCOC(C)=O)=O)(CC(OCOC(C)=O)=O)C=1C=C2C(C=C(O2)C=3OC(C(OCOC(C)=O)=O)=CN3)=CC1OCCOC4=C(N(CC(OCOC(C)=O)=O)CC(OCOC(C)=O)=O)C=CC(C)=C4

Synonyms:

• 5-Oxazolecarboxylic acid, 2-[6-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-[2-[2-[bis[2-[(acetyloxy)methoxy]-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-2-benzofuranyl]-, (acetyloxy)methyl ester
• Acetoxymethyl 2-[5-[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]-4-[2-[2-[Bis[2-(Acetoxymethoxy)-2-Oxo-Ethyl]Amino]-5-Methyl-Phenoxy]Ethoxy]Benzofuran-2-Yl]Oxazole-5-Carboxylate
• FURA 2/AM in Solution
• FURA2/AM *1SET = 10x100UG**
• Fura 2 acetoxymethyl ester
• Fura 2-Am Yellow Powder
• Fura 2AM
• Fura2-AM

FURA 2-AM

CAS: 108964-32-5

A calcium indicator; derivative of Fura-2 used to load the chelator into cells This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code o

Formula: C₄₄H₄₇N₃O₂₄

Color and Shape: Powder, Pale cream to yellow

Molecular weight: 1001.86

Ref: 02-J62728

Bis(acetoxymethyl) 2,2'-((2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)-5-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)benzofuran-6-yl)azanediyl)diacetate

CAS: 108964-32-5

Formula: C₄₄H₄₇N₃O₂₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 1001.8497

Ref: IN-DA007TSU

Bis(acetoxymethyl) 2,2'-((2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)-5-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)benzofuran-6-yl)azanediyl)diacetate

CAS: 108964-32-5

Bis(acetoxymethyl) 2,2'-((2-(5-((acetoxymethoxy)carbonyl)oxazol-2-yl)-5-(2-(2-(bis(2-(acetoxymethoxy)-2-oxoethyl)amino)-5-methylphenoxy)ethoxy)benzofuran-6-yl)azanediyl)diacetate

Purity: 98%

Molecular weight: 1001.86g/mol

Ref: 54-OR1067089

Fura-2 AM

CAS: 108964-32-5

Fura-2 AM is an indicator of ratiometric fluorescent Ca2+.

Formula: C₄₄H₄₇N₃O₂₄

Purity: 98.05%

Color and Shape: Solid

Molecular weight: 1001.85

Ref: TM-T18995

Fura 2-AM

CAS: 108964-32-5

Formula: C₄₄H₄₇N₃O₂₄

Purity: ≥ 95.0%

Color and Shape: Yellow to yellow-green powder or solid

Molecular weight: 1001.87

Ref: 7W-GK3824

Fura-2(AM)

CAS: 108964-32-5

Purity: >95%

Molecular weight: 1001.857

Ref: 10-M01747