CAS 1089736-73-1

N-(1-Oxopentyl-2,2,3,3,4,4,5,5,5-d₉)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-<span class="text-smallcaps">L</span>-valine

Description:

N-(1-Oxopentyl-2,2,3,3,4,4,5,5,5-d9)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine is a complex organic compound characterized by its unique structural features, including a valine amino acid backbone, a pentyl chain, and a tetrazole moiety. The presence of deuterium atoms in the pentyl chain indicates that this compound is isotopically labeled, which can be useful in various analytical applications, including pharmacokinetics and metabolic studies. The biphenyl group contributes to the compound's hydrophobic characteristics, potentially influencing its solubility and interaction with biological membranes. The tetrazole ring is known for its biological activity and can enhance the compound's pharmacological properties. Overall, this compound's intricate structure suggests potential applications in medicinal chemistry, particularly in drug design and development, where modifications to amino acids and incorporation of heterocycles can lead to improved efficacy and selectivity in therapeutic agents.

Formula: C₂₄H₂₀D₉N₅O₃

InChI: InChI=1S/C24H29N5O3/c1-4-5-10-21(30)29(22(16(2)3)24(31)32)15-17-11-13-18(14-12-17)19-8-6-7-9-20(19)23-25-27-28-26-23/h6-9,11-14,16,22H,4-5,10,15H2,1-3H3,(H,31,32)(H,25,26,27,28)/t22-/m0/s1/i1D3,4D2,5D2,10D2

InChI key: InChIKey=ACWBQPMHZXGDFX-KDDXQTGLSA-N

SMILES: C(N([C@@H](C(C)C)C(O)=O)C(C(C(C(C([2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])=O)C1=CC=C(C2=C(C=CC=C2)C=3NN=NN3)C=C1

Synonyms:

• N-(1-Oxopentyl-2,2,3,3,4,4,5,5,5-d9)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine
• L-Valine, N-(1-oxopentyl-2,2,3,3,4,4,5,5,5-d9)-N-[[2′-(2H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-
• Valsartan D9Q: What is
• Valsartan D9 Q: What are the applications of
• Valsartan D9
• L-Valine, N-(1-oxopentyl-d9)-N-[[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]Methyl]-
• ACWBQPMHZXGDFX-KDDXQTGLSA-N
• VALSARTAN-D9 (D7-D9 MIXTURE)
• (2S)-3-methyl-2-[2,2,3,3,4,4,5,5,5-nonadeuteriopentanoyl-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]amino]butanoic acid
• [2H9]-Valsartan (mixture)
• Valsartan D9 Q: What is the storage condition of
• Valsartan D9 Q: What is the CAS Number of
• rac-Valsartan D9

rac-Valsartan-d9

CAS: 1089736-73-1

Formula: C₂₄H₂₀D₉N₅O₃

Color and Shape: White To Off-White Solid

Molecular weight: 444.58

Ref: 4Z-V-022

Valsartan-d9

CAS: 1089736-73-1

Formula: C₂₄H₂₀D₉N₅O₃

Color and Shape: White To Off-White Solid

Molecular weight: 444.58

Ref: 4Z-V-0248

Valsartan-d9

CAS: 1089736-73-1

Valsartan D9: deuterium-labeled, angiotensin II receptor antagonist, treats hypertension & heart failure.

Formula: C₂₄H₂₉N₅O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 444.57

Ref: TM-T13282

Valsartan-d9 (Major)

Controlled Product

CAS: 1089736-73-1

Applications An isotopically labelled version of Valsartan (V095750), a nonpeptide angiotensin II AT1-receptor antagonist. Antihypertensive.
References Criscione, L., et al.: Brit. J. Pharmacol., 110, 761 (1993), Muller, P., et al.: Eur. J. Clin. Pharmacol., 47, 231 (1994)

Formula: C₂₄H₂₀D₉N₅O₃

Color and Shape: Off White

Molecular weight: 444.57

Ref: TR-V095753

Valsartan-D9

CAS: 1089736-73-1

Formula: C₂₄H₂₀D₉N₅O₃

Molecular weight: 444.6

Ref: ST-EA-CP-V3056