CAS 109-12-6

2-Aminopyrimidine

Description:

2-Aminopyrimidine is an organic compound characterized by a pyrimidine ring with an amino group attached at the second position. Its molecular formula is C4H5N3, and it features a six-membered aromatic ring containing two nitrogen atoms at positions 1 and 3. This compound is typically a colorless to pale yellow solid that is soluble in water and polar organic solvents. 2-Aminopyrimidine exhibits basic properties due to the presence of the amino group, allowing it to participate in various chemical reactions, including nucleophilic substitutions and condensation reactions. It is often used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other nitrogen-containing compounds. Additionally, 2-aminopyrimidine can act as a building block in the development of biologically active molecules, including those with potential antiviral and anticancer properties. Its reactivity and structural features make it a valuable compound in organic synthesis and medicinal chemistry.

Formula: C₄H₅N₃

InChI: InChI=1S/C4H5N3/c5-4-6-2-1-3-7-4/h1-3H,(H2,5,6,7)

InChI key: InChIKey=LJXQPZWIHJMPQQ-UHFFFAOYSA-N

SMILES: NC=1N=CC=CN1

Synonyms:

• 1,2-Dihydro-2-iminopyrimidine
• 2-Amino-1,3-diazine
• 2-Aminopyrimide
• 2-Aminopyrimidin
• 2-Pyrimidinamine
• 2-Pyrimidylamine
• Aminopyrimidine, 2-
• Nsc 1912
• Pirimidin-2-Ilamina
• Pyrimidin-2-Amine
• Pyrimidin-2-Ylamine
• Pyrimidin-2-ylamin
• Pyrimidine, 1,2-dihydro-2-imino-
• Pyrimidine, 2-amino-
• Pyrimidine-2-Ylamine

2-Aminopyrimidine

CAS: 109-12-6

Formula: C₄H₅N₃

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 95.11

Ref: 3B-A0412

2-Aminopyrimidine, 98%

CAS: 109-12-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₄H₅N₃

Purity: 98%

Color and Shape: White to cream to pale yellow, Crystals or powder or crystalline powder

Molecular weight: 95.11

Ref: 02-B24594

SULFADIAZINE IMPURITY A CRS

CAS: 109-12-6

SULFADIAZINE IMPURITY A CRS

Formula: C₄H₅N₃

Molecular weight: 95.1026

Ref: 41-Y0001469

2-Aminopyrimidine

CAS: 109-12-6

Formula: C₄H₅N₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 95.1026

Ref: IN-DA00334G

2-Aminopyrimidine

CAS: 109-12-6

Formula: C₄H₅N₃

Molecular weight: 95.11

Ref: 7W-GK0837

2-Aminopyrimidine

CAS: 109-12-6

2-Aminopyrimidine

Formula: C₄H₅N₃

Purity: 97%

Color and Shape: faint yellow crystalline solid

Molecular weight: 95.10g/mol

Ref: 54-OR5847

2-Aminopyrimidine

CAS: 109-12-6

Formula: C₄H₅N₃

Color and Shape: White To Off-White Solid

Molecular weight: 95.11

Ref: 4Z-P-212018

Sulfadiazine EP Impurity A

Controlled Product

CAS: 109-12-6

Formula: C₄H₅N₃

Color and Shape: Neat

Molecular weight: 95.10

Ref: 86-MM0623.03

2-Aminopyrimidine

CAS: 109-12-6

Applications 2-Aminopyrimidine is used in the synthesis of sulfonamides as isoform-selective inhibitors with efficacy in rodent pain models.
References Focken, T. et al.: ACS Med. Chem., 7, 277 (2016); Reddy, M. et al.: Bioorg. Med. Chem., 24, 521 (2016);

Formula: C₄H₅N₃

Color and Shape: Neat

Molecular weight: 95.1

Ref: TR-A629255

2-Pyrimidin-4,6-d3-amine

Controlled Product

CAS: 109-12-6

Applications 2-​Pyrimidin-​4,​6-​d3-​amine is a byproduct in the synthesis of 2-Chloropyrimidine-d3 (C380852), which was used in the study of IR vibrational spectroscopy of [Ru(bpy)2(bpm)]2+ and [Ru(bpy)3]2+ in the excited triplet state.
References Mukuta, T., et al.: Inorg. Chem., 53, 2481 (2014)

Formula: C₄D₂H₃N₃

Color and Shape: Neat

Molecular weight: 97.115

Ref: TR-A629257

2-Aminopyrimidine

CAS: 109-12-6

Formula: C₄H₅N₃

Purity: 96%

Color and Shape: Light yellow powder

Molecular weight: 95.105

Ref: 10-F036344

2-Aminopyrimidine

CAS: 109-12-6

2-Aminopyrimidine is an organic compound that belongs to the group of pyridines. It has been shown to have antimicrobial, antitumor, and antiviral properties. 2-Aminopyrimidine has been used as a fungicide and herbicide in horticulture and agriculture, respectively. The molecular geometry of this molecule is octahedral with coordination geometry C2v. This chemical binds to the BCR-ABL kinase receptor and inhibits its activity by competitive inhibition of ATP binding. 2-Aminopyrimidine has been shown to have a hematologic response in vivo models and in vitro assays. It also has anti-inflammatory effects when it is taken orally or applied topically.

Formula: C₄H₅N₃

Purity: Min. 95%

Molecular weight: 95.1 g/mol

Ref: 3D-FA34676

Sulfadiazine EP Impurity A

CAS: 109-12-6

Formula: C₄H₅N₃

Molecular weight: 95.10

Ref: ST-EA-CP-S54001