CAS 1090-78-4

N,N-Dimethyl-10H-phenothiazine-2-sulfonamide

Description:

N,N-Dimethyl-10H-phenothiazine-2-sulfonamide, with the CAS number 1090-78-4, is a chemical compound that belongs to the phenothiazine class, which is characterized by a tricyclic structure containing sulfur and nitrogen atoms. This compound features a sulfonamide group, which contributes to its solubility and reactivity. It is typically a solid at room temperature and may exhibit a yellow to brown coloration. The presence of the dimethyl groups enhances its lipophilicity, potentially influencing its biological activity and interaction with cellular membranes. N,N-Dimethyl-10H-phenothiazine-2-sulfonamide is known for its applications in medicinal chemistry, particularly as an antipsychotic and antimicrobial agent. Its mechanism of action often involves the modulation of neurotransmitter systems, particularly dopamine receptors. Additionally, the sulfonamide moiety can impart antibacterial properties, making it relevant in the development of therapeutic agents. Safety and handling precautions are essential due to potential toxicity and environmental impact, as with many compounds in this class.

Formula: C₁₄H₁₄N₂O₂S₂

InChI: InChI=1S/C14H14N2O2S2/c1-16(2)20(17,18)10-7-8-14-12(9-10)15-11-5-3-4-6-13(11)19-14/h3-9,15H,1-2H3

InChI key: InChIKey=KMMXCCWCGOUAGH-UHFFFAOYSA-N

SMILES: S(N(C)C)(=O)(=O)C=1C=C2C(SC=3C(N2)=CC=CC3)=CC1

Synonyms:

• 10H-Phenothiazine-2-sulfonamide, N,N-dimethyl-
• 2-Dimethyl Amino Sulfonyl Phenthiazine
• 2-Dimethylsulfonamidophenothiazine
• 2-Dimethylsulphamoylphenothiazine
• N,N-dimethyl-10H-phenothiazine-2-sulfonamide
• Phenothiazine-2-sulfonamide, N,N-dimethyl-

2-Dimethyl amino sulfonyl phenthiazine

CAS: 1090-78-4

Formula: C₁₄H₁₄N₂O₂S₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 306.4032

Ref: IN-DA008SMQ

N,N-Dimethyl-10H-phenothiazine-2-sulfonamide

CAS: 1090-78-4

N,N-Dimethyl-10H-phenothiazine-2-sulfonamide

Purity: 95%

Ref: 54-OR1038675

2-Dimethylsulfonamidophenothiazine

Controlled Product

CAS: 1090-78-4

Applications 2-Dimethylsulfonamidophenothiazine is a derivative of Phenothiazine (P318040), a key component of antipsychotic and antihistaminic drugs.
References Bansode, T., et al.: Eur. J. Med. Chem., 44, 5094 (2009); Baell, J., et al.: J. Med. Chem., 53, 2719 (2010); Howard, P., et al.: Environ. Sci. Technol., 44, 2277 (2010); Koren, J., et al.: J. Biol. Chem., 285, 2498 (2010); Amobi, N., et al.: Eur. J. Pharmacol., 627, 285 (2010),

Formula: C₁₄H₁₄N₂O₂S₂

Color and Shape: Neat

Molecular weight: 306.4

Ref: TR-D461665