CAS 109032-22-6
:4-HYDROXY NIMESULIDE
Description:
4-Hydroxy Nimesulide is a non-steroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic and anti-inflammatory properties. It is a derivative of nimesulide, which is known for its selective inhibition of cyclooxygenase-2 (COX-2), an enzyme involved in the inflammatory process. The chemical structure of 4-Hydroxy Nimesulide features a hydroxyl group (-OH) at the para position of the aromatic ring, which enhances its pharmacological activity. This compound is typically characterized by its moderate solubility in organic solvents and limited solubility in water, which can affect its bioavailability. It is often utilized in the treatment of pain and inflammation associated with various conditions, including osteoarthritis and musculoskeletal disorders. Additionally, 4-Hydroxy Nimesulide has been studied for its potential antioxidant properties, which may contribute to its therapeutic effects. As with other NSAIDs, it is important to consider potential side effects, including gastrointestinal issues and cardiovascular risks, when using this medication.
Formula:C13H12N2O6S
InChI:InChI=1/C13H12N2O6S/c1-22(19,20)14-12-7-2-9(15(17)18)8-13(12)21-11-5-3-10(16)4-6-11/h2-8,14,16H,1H3
SMILES:CS(=O)(=O)Nc1ccc(cc1Oc1ccc(cc1)O)N(=O)=O
Synonyms:- N-[2-(4-Hydroxyphenoxy)-4-nitrophenyl]-methanesulfonamide
- 4-Nitro-2-(4'-Hydroxyphenoxy)Methanesulfonanilide
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Found 4 products.
4’-Hydroxy Nimesulide
CAS:Controlled Product<p>Applications The main metabolite of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Facino, R.M., et al.: Drugs, 46 (Suppl1),15 (1993), Westphal, J., et al.: J. Antimicrob. Chemother., 33, 387 (1994), Castell, J., et al.: Cell Biol. Toxicol., 13, 331 (1997), Georges, H., et al.: Life Sci., 65, 151 (1999), Singla, A.K., et al.: J. Pharm. Pharmacol., 52, 467 (2000),<br></p>Formula:C13H12N2O6SColor and Shape:White To Light BrownMolecular weight:324.31
