CAS 109053-20-5

L-Histidine,1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-,pentafluorophenyl ester

Description:

L-Histidine, 1-[(1,1-dimethylethoxy)carbonyl]-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, pentafluorophenyl ester, identified by CAS number 109053-20-5, is a complex organic compound primarily used in peptide synthesis and as a protecting group in organic chemistry. This substance features a histidine backbone, which is an essential amino acid known for its role in protein synthesis and various metabolic processes. The presence of the 1,1-dimethylethoxycarbonyl and 9H-fluoren-9-ylmethoxycarbonyl groups indicates that it is designed for selective protection of functional groups during chemical reactions, enhancing the stability and reactivity of the histidine residue. The pentafluorophenyl ester moiety contributes to the compound's reactivity and solubility characteristics, making it suitable for various synthetic applications. Overall, this compound exemplifies the intricate design often employed in peptide chemistry, where protecting groups are crucial for achieving desired reaction outcomes while minimizing side reactions.

Formula: C₃₂H₂₆F₅N₃O₆

Fmoc-His(Boc)-OPfp

CAS: 109053-20-5

Bachem ID: 4015229.

Formula: C₃₂H₂₆F₅N₃O₆

Color and Shape: White Powder

Molecular weight: 643.57

Ref: 01-4015229

Fmoc-His(Boc)-OPfp

CAS: 109053-20-5

The Fmoc-His(Boc)-OPfp is a synthetic peptide that has been shown to bind to angiotensin. It is chemically reactive and can be used in diagnostic assays for the detection of angiotensin. The Fmoc-His(Boc)-OPfp can also be used as a feedback control for sequence analysis, where it monitors the reaction sequence by binding to the last amino acid in the peptide. This binding prevents the formation of an enzyme with the enzyme reaction necessary for cell wall biosynthesis, inhibiting protein synthesis and cell division.

Formula: C₃₂H₂₆F₅N₃O₆

Purity: Min. 95%

Molecular weight: 643.56 g/mol

Ref: 3D-FF111302