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CAS 109074-94-4

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FMOC-PRO-OSU

Description:
FMOC-PRO-OSU, or 9-fluorenylmethoxycarbonyl-proline N-hydroxysuccinimide ester, is a chemical compound commonly used in peptide synthesis and bioconjugation. It features a protective FMOC (9-fluorenylmethoxycarbonyl) group, which is widely utilized to protect amino groups during the synthesis of peptides. The proline component provides structural diversity and can influence the conformation of peptides. The N-hydroxysuccinimide (OSU) moiety enhances the reactivity of the compound, allowing for efficient coupling reactions with amines, which is crucial in the formation of peptide bonds. FMOC-PRO-OSU is typically characterized by its stability under basic conditions and its ability to be deprotected under mild acidic conditions, making it a versatile reagent in organic synthesis. Its applications extend to the development of pharmaceuticals, where precise peptide sequences are essential for biological activity. Overall, FMOC-PRO-OSU is valued for its role in facilitating the synthesis of complex peptide structures in a controlled manner.
Formula:C24H22N2O6
InChI:InChI=1/C24H22N2O6/c27-21-11-12-22(28)26(21)32-23(29)20-10-5-13-25(20)24(30)31-14-19-17-8-3-1-6-15(17)16-7-2-4-9-18(16)19/h1-4,6-9,19-20H,5,10-14H2
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=O)N1CCCC1C(=O)ON1C(=O)CCC1=O
Synonyms:
  • Fmoc-L-Proline Hydroxysuccinimide Ester
  • Fmoc-L-Proline N-Hydroxysuccinimide Ester
  • NALPHA-9-Fluorenylmethoxycarbonyl-L-proline N-hydroxysuccinimide ester
  • Fmoc-L-Pro-OSu
  • N-alpha-(9-Fluorenylmethyloxycarbonyl)-L-proline succinimidyl ester
  • Fmoc-L-Proline Hydroxysuccinimidester
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