CAS 109113-72-6

2-(Chloromethyl)-4-methylquinazoline

Description:

2-(Chloromethyl)-4-methylquinazoline is a chemical compound characterized by its quinazoline core structure, which consists of a fused benzene and pyrimidine ring. This compound features a chloromethyl group (-CH2Cl) at the 2-position and a methyl group (-CH3) at the 4-position of the quinazoline ring. It is typically a solid at room temperature and may exhibit moderate solubility in organic solvents. The presence of the chloromethyl group suggests potential reactivity, making it a useful intermediate in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. The compound may also exhibit biological activity, which can be explored in medicinal chemistry. Safety data indicates that, like many chlorinated compounds, it should be handled with care due to potential toxicity and environmental concerns. Proper storage conditions and protective measures are recommended to mitigate risks associated with exposure. Overall, 2-(Chloromethyl)-4-methylquinazoline is a versatile compound with applications in various chemical research fields.

Formula: C₁₀H₉ClN₂

InChI: InChI=1S/C10H9ClN2/c1-7-8-4-2-3-5-9(8)13-10(6-11)12-7/h2-5H,6H2,1H3

InChI key: InChIKey=UHCUBOJGMLASBY-UHFFFAOYSA-N

SMILES: CC=1C2=C(N=C(CCl)N1)C=CC=C2

Synonyms:

• 2-(Chloromethyl)-4-methylquinazoline
• 2-chloromethyl-4-methyl Quinazoline
• NSC 48971
• Quinazoline, 2-(chloromethyl)-4-methyl-

2-(Chloromethyl)-4-methylquinazoline (Quinazoline, 2-(chloromethyl)-4-methyl)

CAS: 109113-72-6

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₁₀H₉ClN₂

Color and Shape: White Off-White Solid

Molecular weight: 192.04543

Ref: 45-1A04850

2-(Chloromethyl)-4-methylquinazoline

CAS: 109113-72-6

Formula: C₁₀H₉ClN₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 192.6449

Ref: IN-DA0039Q0

Linagliptin Impurity 44

CAS: 109113-72-6

Formula: C₁₀H₉ClN₂

Color and Shape: Pale Yellow Solid

Molecular weight: 192.65

Ref: 4Z-L-4457

2-(Chloromethyl)-4-methylquinazoline

CAS: 109113-72-6

Formula: C₁₀H₉ClN₂

Purity: >98.0%(GC)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 192.65

Ref: 3B-C2928

2-(Chloromethyl)-4-methylquinazoline

CAS: 109113-72-6

2-(Chloromethyl)-4-methylquinazoline

Purity: 98%

Color and Shape: Solid

Molecular weight: 192.65g/mol

Ref: 54-OR918316

2-(Chloromethyl)-4-methylquinazoline

Controlled Product

CAS: 109113-72-6

Impurity Linagliptin 2-Chloromethyl Impurity
Applications 2-(Chloromethyl)-4-methylquinazoline, is a building block used for the preparation of Linagliptin (L465900), and its impurities, acting as type 2 diabetes drugs.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Prabavathy, N. et al.: Int. J. Pharm. Bio. Sci., 2, 438 (2011); Deacon, C.F.: Diab. Obes. Metab., 13, 7 (2011);

Formula: C₁₀H₉ClN₂

Color and Shape: Neat

Molecular weight: 192.64

Ref: TR-C369850

Linagliptin 2-Chloromethyl Impurity

CAS: 109113-72-6

Formula: C₁₀H₉ClN₂

Molecular weight: 192.64

Ref: ST-EA-CP-L1013

2-(Chloromethyl)-4-methylquinazoline

CAS: 109113-72-6

Formula: C₁₀H₉ClN₂

Purity: 95%

Color and Shape: Very pale yellow to reddish yellow powder

Molecular weight: 192.65

Ref: 10-F092815

2-(Chloromethyl)-4-methylquinazoline

CAS: 109113-72-6

Inhibitor of SIRT1 deacetylase

Formula: C₁₀H₉ClN₂

Purity: Min. 95%

Color and Shape: Off-White To Yellow Solid

Molecular weight: 192.64 g/mol

Ref: 3D-FC32821