CAS: 1092364-38-9 - 1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one

Formula: C₂₃H₂₁Cl₂FN₄O₃

InChI: InChI=1S/C23H21Cl2FN4O3/c1-3-20(31)30-8-6-13(7-9-30)33-19-10-14-17(11-18(19)32-2)27-12-28-23(14)29-16-5-4-15(24)21(25)22(16)26/h3-5,10-13H,1,6-9H2,2H3,(H,27,28,29)

InChI key: InChIKey=LPFWVDIFUFFKJU-UHFFFAOYSA-N

SMILES: O=C(C=C)N1CCC(OC2=CC=3C(=NC=NC3NC4=CC=C(Cl)C(Cl)=C4F)C=C2OC)CC1

Synonyms:

• 1-[4-[4-(3,4-Dichloro-2-fluoroanilino)-7-methoxyquinazolin-6-yl]oxypiperidin-1-yl]prop-2-en-1-one
• 2-Propen-1-one, 1-[4-[[4-[(3,4-dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-
• Poziotinib

1-[4-[[4-[(3,4-Dichloro-2-fluorophenyl)amino]-7-methoxy-6-quinazolinyl]oxy]-1-piperidinyl]-2-propen-1-one

CAS: 1092364-38-9

• Formula: C₂₃H₂₁Cl₂FN₄O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 491.3422

Poziotinib

CAS: 1092364-38-9

Poziotinib (NOV120101)(NOV120101; HM781-36B) is an irreversible HER1/2/4 inhibitor (IC50s: 3/5/23 nM).

• Formula: C₂₃H₂₁Cl₂FN₄O₃
• Purity: 97.81% - 99.78%
• Color and Shape: Solid
• Molecular weight: 491.34

Poziotinib

CAS: 1092364-38-9

• Formula: C₂₃H₂₁Cl₂FN₄O₃
• Color and Shape: Neat
• Molecular weight: 491.34

Poziotinib

CAS: 1092364-38-9

Inhibitor of EGFR receptor

• Formula: C₂₃H₂₁Cl₂FN₄O₃
• Purity: Min. 95%
• Molecular weight: 491.34 g/mol