CAS 1092443-55-4

(2S,3S)-3-[[3-(1-Methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-1,2,4-butanetriol

Description:

The chemical substance known as (2S,3S)-3-[[3-(1-Methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-1,2,4-butanetriol, with the CAS number 1092443-55-4, is a complex organic compound characterized by its specific stereochemistry and functional groups. It features a butanetriol backbone, which contributes to its potential biological activity, particularly in medicinal chemistry. The presence of a pyrazolo[1,5-a]pyrimidine moiety suggests that it may interact with various biological targets, possibly acting as an inhibitor or modulator in biochemical pathways. The compound also contains an isopropyl group and a phenylmethyl amino substituent, which may enhance its lipophilicity and influence its pharmacokinetic properties. Overall, this substance is of interest in pharmaceutical research, particularly for its potential therapeutic applications, although detailed studies would be necessary to elucidate its mechanism of action and efficacy in biological systems.

Formula: C₂₀H₂₇N₅O₃

InChI: InChI=1S/C20H27N5O3/c1-13(2)15-10-22-25-19(21-9-14-6-4-3-5-7-14)8-18(24-20(15)25)23-16(11-26)17(28)12-27/h3-8,10,13,16-17,21,26-28H,9,11-12H2,1-2H3,(H,23,24)/t16-,17+/m0/s1

InChI key: InChIKey=KRIWIRSMQRQYJG-DLBZAZTESA-N

SMILES: C(C)(C)C1=C2N(C(NCC3=CC=CC=C3)=CC(N[C@H]([C@@H](CO)O)CO)=N2)N=C1

Synonyms:

• (2S,3S)-3-[[3-(1-Methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-1,2,4-butanetriol
• 1,2,4-Butanetriol, 3-[[3-(1-methylethyl)-7-[(phenylmethyl)amino]pyrazolo[1,5-a]pyrimidin-5-yl]amino]-, (2S,3S)-
• BS 194
• CS-2655
• BS194
• (2S,3S)-3-(7-(benzylaMino)-3-isopropylpyrazolo[1,5-a]pyriMidin-5-ylaMino)butane-1,2,4-triol
• BS-194;BS 194

BS194

CAS: 1092443-55-4

BS194

Purity: ≥98%

Molecular weight: 385.46g/mol

Ref: 54-BUP02870

BS194

CAS: 1092443-55-4

BS194 is as a potent cyclin-dependent protein kinases (CDKs) inhibitor.

Formula: C₂₀H₂₇N₅O₃

Purity: 99.85%

Color and Shape: Solid

Molecular weight: 385.46

Ref: TM-T7698

BS194

CAS: 1092443-55-4

BS194 is a compound that inhibits the activity of protein kinase C. It has been shown to inhibit the phosphorylation of the Alzheimer's disease-associated tau protein and colorectal carcinoma cells. BS194 has also been shown to have positive effects on cardiovascular disorders, such as hypertension and myocardial infarction. The pharmacokinetic profile of this drug was analyzed in mice with leukemia. BS194 was found to be homologous to a number of other compounds, including bryostatin 1, which is used for cancer therapy. The homology between these two compounds has been confirmed by analyzing the binding affinity and inhibitory phosphorylation profiles of these compounds.

Formula: C₂₀H₂₇N₅O₃

Purity: Min. 95%

Molecular weight: 385.5 g/mol

Ref: 3D-STB44355