CAS 1092457-65-2

D-Leucine, D-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide)

Description:

D-Leucine, D-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide) is a complex cyclic peptide characterized by its unique arrangement of amino acids and disulfide bonds. This compound features both D- and L-amino acids, which contribute to its structural diversity and potential biological activity. The cyclic nature of the molecule, indicated by the disulfide linkages, enhances its stability and may influence its interaction with biological targets. The presence of multiple cysteine residues allows for the formation of disulfide bridges, which are crucial for maintaining the three-dimensional conformation of the peptide. Such cyclic peptides often exhibit significant pharmacological properties, including antimicrobial, antiviral, or anticancer activities, making them of interest in medicinal chemistry and drug development. The specific arrangement of amino acids and the cyclic structure can also affect the peptide's solubility, bioavailability, and overall efficacy in biological systems.

Formula: C₆₅H₁₀₄N₁₈O₂₆S₄

Synonyms:

• Dolcanatide
• D-Leucine, D-asparaginyl-L-α-aspartyl-L-α-glutamyl-L-cysteinyl-L-α-glutamyl-L-leucyl-L-cysteinyl-L-valyl-L-asparaginyl-L-valyl-L-alanyl-L-cysteinyl-L-threonylglycyl-L-cysteinyl-, cyclic (4→12),(7→15)-bis(disulfide)

Dolcanatide

CAS: 1092457-65-2

Dolcanatide: oral GC-C agonist with laxative, pain-relief, and anti-inflammatory properties for IBD research.

Formula: C₆₅H₁₀₄N₁₈O₂₆S₄

Color and Shape: Solid

Molecular weight: 1681.89

Ref: TM-T76274