CAS 109273-98-5

Dehydromonacolin K

Description:

Dehydromonacolin K, with the CAS number 109273-98-5, is a naturally occurring compound primarily derived from the fermentation of rice by the mold Monascus purpureus. It is a member of the monacolin family, which includes various compounds known for their potential cholesterol-lowering effects. Dehydromonacolin K is structurally related to lovastatin, a well-known statin used in clinical settings to manage hyperlipidemia. This compound exhibits properties that may inhibit the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol biosynthesis. In addition to its lipid-lowering effects, Dehydromonacolin K has garnered interest for its potential antioxidant and anti-inflammatory activities. It is typically found in dietary supplements and functional foods, often marketed for cardiovascular health. However, as with any bioactive compound, the efficacy and safety of Dehydromonacolin K can vary based on dosage, formulation, and individual health conditions, necessitating further research to fully understand its therapeutic potential and mechanisms of action.

Formula: C₂₄H₃₄O₄

InChI: InChI=1S/C24H34O4/c1-5-16(3)24(26)28-21-14-15(2)13-18-10-9-17(4)20(23(18)21)12-11-19-7-6-8-22(25)27-19/h6,8-10,13,15-17,19-21,23H,5,7,11-12,14H2,1-4H3/t15-,16-,17-,19-,20-,21-,23-/m0/s1

InChI key: InChIKey=SPIVMHAGTHFLMO-OCAGQIGWSA-N

SMILES: O(C([C@H](CC)C)=O)[C@@H]1[C@]2(C(C=C[C@H](C)[C@@H]2CC[C@H]3OC(=O)C=CC3)=C[C@H](C)C1)[H]

Synonyms:

• Butanoic acid, 2-methyl-, 8-[2-(3,6-dihydro-6-oxo-2H-pyran-2-yl)ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, [1S-[1α(R*),3α,7β,8β(S*),8aβ]]-
• L 642257
• Dehydrolovastatin
• Dehydromonacolin K
• Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, (2S)-
• (S)-(1S,3R,7S,8S,8aR)-3,7-dimethyl-8
• Lovastatin EP Impurity C (Anhydro Lovastatin)
• alpha,beta-Dehydrolovastatin
• Anhydro Lovastatin Lactone Q: What is the CAS Number of
• Dehydro lovastatin Solution in Methanol, 100μg/mL
• Lovastatin EP IMpurity C
• [(1S,3R,7S,8S,8aR)-3,7-dimethyl-8-[2-[(2R)-6-oxo-2,3-dihydropyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
• Anhydro Lovastatin Lactone Q: What is the storage condition of
• Anhydro Lovastatin LactoneQ: What is
• Chlordiazepoxide Solution, 100ppm
• Lovastatin Impurity 3(Lovastatin EP Impurity C)
• Anhydro Lovastatin Lactone
• 2',3'-Anhydromonacolin K
• Lovastatin EP Impurity C (Dehydro Lovastatin)
• (1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-[2
• (2S)-(1S,3R,7S,8S)-3,7-dimethyl-8-(2-((R)-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2-methylbutanoate
• Anhydro Lovastatin Lactone Q: What are the applications of
• Lovastatin impurity C

Lovastatin EP Impurity C (Dehydro Lovastatin)

CAS: 109273-98-5

Formula: C₂₄H₃₄O₄

Color and Shape: White To Off-White Solid

Molecular weight: 386.53

Ref: 4Z-L-1215

Lovastatin EP Impurity C

CAS: 109273-98-5

Formula: C₂₄H₃₄O₄

Color and Shape: Neat

Molecular weight: 386.52

Ref: 86-MM0050.03

Dehydrolovastatin

CAS: 109273-98-5

Formula: C₂₄H₃₄O₄

Color and Shape: Neat

Molecular weight: 386.52

Ref: 04-C12116000

Dehydro Lovastatin

Controlled Product

CAS: 109273-98-5

Impurity Lovastatin EP Impurity C
Stability Light Sensitive
Applications Dehydro Lovastatin (Lovastatin EP Impurity C) is a Lovastatin impurity.
References Duggan, D., et al.: Drug Metab. Dispos., 17, 166 (1989), Wang-Iverson, D., et al.: Drugs, 23, 127 (1994), Wu, Y., et al.: J. Pharm. Biomed. Anal., 20, 471 (1999),

Formula: C₂₄H₃₄O₄

Color and Shape: White

Molecular weight: 386.52

Ref: TR-D229685

Lovastatin EP Impurity C

CAS: 109273-98-5

Formula: C₂₄H₃₄O₄

Molecular weight: 386.53

Ref: ST-EA-CP-L76025