CAS 109273-98-5: Dehydromonacolin K

Description: Dehydromonacolin K, with the CAS number 109273-98-5, is a naturally occurring compound primarily derived from the fermentation of rice by the mold Monascus purpureus. It is a member of the monacolin family, which includes various compounds known for their potential cholesterol-lowering effects. Dehydromonacolin K is structurally related to lovastatin, a well-known statin used in clinical settings to manage hyperlipidemia. This compound exhibits properties that may inhibit the enzyme HMG-CoA reductase, which plays a crucial role in cholesterol biosynthesis. In addition to its lipid-lowering effects, Dehydromonacolin K has garnered interest for its potential antioxidant and anti-inflammatory activities. It is typically found in dietary supplements and functional foods, often marketed for cardiovascular health. However, as with any bioactive compound, the efficacy and safety of Dehydromonacolin K can vary based on dosage, formulation, and individual health conditions, necessitating further research to fully understand its therapeutic potential and mechanisms of action.

Formula: C₂₄H₃₄O₄

InChI: InChI=1S/C24H34O4/c1-5-16(3)24(26)28-21-14-15(2)13-18-10-9-17(4)20(23(18)21)12-11-19-7-6-8-22(25)27-19/h6,8-10,13,15-17,19-21,23H,5,7,11-12,14H2,1-4H3/t15-,16-,17-,19-,20-,21-,23-/m0/s1

InChI key: InChIKey=SPIVMHAGTHFLMO-OCAGQIGWSA-N

SMILES: O=C1OC(CC=C1)CCC2C(C=CC3=CC(C)CC(OC(=O)C(C)CC)C32)C

Synonyms:

• Butanoic acid, 2-methyl-, 8-[2-(3,6-dihydro-6-oxo-2H-pyran-2-yl)ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, [1S-[1α(R*),3α,7β,8β(S*),8aβ]]-
• L 642257
• Dehydrolovastatin
• Dehydromonacolin K
• Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-8-[2-[(2R)-3,6-dihydro-6-oxo-2H-pyran-2-yl]ethyl]-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-1-naphthalenyl ester, (2S)-

Lovastatin EP Impurity C (Dehydro Lovastatin)

CAS: 109273-98-5

• Formula: C₂₄H₃₄O₄
• Color and Shape: White To Off-White Solid
• Molecular weight: 386.53

Lovastatin EP Impurity C

CAS: 109273-98-5

• Formula: C₂₄H₃₄O₄
• Color and Shape: White
• Molecular weight: 386.52

Dehydrolovastatin

CAS: 109273-98-5

• Formula: C₂₄H₃₄O₄
• Color and Shape: Neat
• Molecular weight: 386.52

Dehydro Lovastatin

CAS: 109273-98-5

Impurity Lovastatin EP Impurity C Stability Light Sensitive Applications Dehydro Lovastatin (Lovastatin EP Impurity C) …

• Formula: C₂₄H₃₄O₄
• Color and Shape: White
• Molecular weight: 386.52