CAS 109351-34-0
:(R)-Terazosin
Description:
(R)-Terazosin is a pharmaceutical compound primarily used as an antihypertensive and an alpha-1 adrenergic antagonist. It is characterized by its chiral nature, with the (R) configuration indicating the specific spatial arrangement of its atoms. The molecular formula of (R)-Terazosin is C19H22N4O4S, and it features a sulfonamide group, which contributes to its pharmacological activity. This compound is typically administered in the form of its hydrochloride salt, enhancing its solubility and bioavailability. (R)-Terazosin works by relaxing blood vessels, thereby lowering blood pressure, and is also effective in treating benign prostatic hyperplasia by alleviating urinary symptoms. Its mechanism of action involves selective inhibition of alpha-1 adrenergic receptors, leading to smooth muscle relaxation. The substance is generally well-tolerated, though it may cause side effects such as dizziness or orthostatic hypotension. As with any medication, it is essential to use (R)-Terazosin under medical supervision to ensure safety and efficacy.
Formula:C19H25N5O4
Synonyms:- Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[(tetrahydro-2-furanyl)carbonyl]-, (R)-
- Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-[[(2R)-tetrahydro-2-furanyl]carbonyl]- (9CI)
- (R)-(4-(4-Amino-6,7-dimethoxyquinazolin-2-yl)piperazin-1-yl)(tetrahydrofuran-2-yl)methanone
- (R)-Terazosin
- Terazosin-002-R
- Methanone, [4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl][(2R)-tetrahydro-2-furanyl]-
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Found 4 products.
(R)-Terazosin
CAS:<p>R-Terazosin is the active R-enantiomer and potent α1-adrenoceptor antagonist (Ki: α1a 6.51 nM, α1b 1.01 nM, α1d 1.97 nM).</p>Formula:C19H25N5O4Purity:98.87% - 98.96%Color and Shape:SolidMolecular weight:387.43(R)-Terazosin
CAS:<p>Terazosin is an alpha-adrenergic receptor antagonist that is used to treat benign prostatic hyperplasia, prostate cancer, and urinary incontinence. It is not a prodrug and does not have any active metabolites. Terazosin inhibits the binding of n-methyl-d-aspartic acid (NMDA) to its receptors in the central nervous system and may act as an NMDA antagonist. Terazosin also binds to soluble guanylate cyclase, which regulates nitric oxide production, leading to relaxation of smooth muscle cells in blood vessels. The drug has been shown to be effective in treating prostate cancer cells in vitro by inhibiting the growth of these cells at concentrations between 10 µM and 1 mM. Terazosin may inhibit the activity of long-term treatment with caco-2 cells at concentrations between 0.1 µM and 100 µM. Terazosin has been shown to bind ferrite at concentrations greater than 100</p>Formula:C19H25N5O4Purity:Min. 95%Molecular weight:387.4 g/mol
