CAS 109384-19-2

4-Hydroxypiperidine-1-carboxylic acid tert-butyl ester

Description:

4-Hydroxypiperidine-1-carboxylic acid tert-butyl ester, with the CAS number 109384-19-2, is a chemical compound that belongs to the class of piperidine derivatives. This compound features a piperidine ring, which is a six-membered saturated nitrogen-containing heterocycle, and is characterized by the presence of a hydroxyl group (-OH) and a carboxylic acid moiety that is esterified with tert-butyl alcohol. The tert-butyl ester group enhances the lipophilicity of the molecule, potentially influencing its solubility and reactivity. This compound is often utilized in organic synthesis and medicinal chemistry due to its structural properties, which may contribute to biological activity. Its hydroxyl group can participate in hydrogen bonding, while the piperidine ring can serve as a basic site, making it a versatile intermediate in the synthesis of various pharmaceuticals and agrochemicals. Safety and handling precautions should be observed, as with any chemical substance, to mitigate risks associated with its use.

Formula: C₁₀H₁₉NO₃

InChI: InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3

InChI key: InChIKey=PWQLFIKTGRINFF-UHFFFAOYSA-N

SMILES: C(OC(C)(C)C)(=O)N1CCC(O)CC1

Synonyms:

• 1,1-Dimethylethyl 4-hydroxypiperidine-1-carboxylate
• 1-(Tert-Butoxycarbonyl)-4-Hydroxypiperidine
• 1-(tert-Butyloxycarbonyl)piperidin-4-ol
• 1-Boc-4-Hydroxypiperidine
• 1-Boc-4-Piperidinol
• 1-Boc-piperidin-4-ol
• 1-N-Boc-4-Hydroxypiperidine
• 1-Piperidinecarboxylic Acid, 4-Hydroxy-,1,1-Dimethylethyl Ester
• 1-Tert-Butoxycarbonyl-4-Piperidinol
• 1-tert-Butyloxycarbonyl-4-hydroxypiperidine
• 2-Methylpropan-2-yl 4-hydroxypiperidine-1-carboxylate
• 4-Hydroxy-1-(tert-butoxycarbonyl)piperidine
• 4-Hydroxy-1-Boc-piperidine
• 4-Hydroxy-1-piperidinecarboxylic acid 1,1-dimethylethyl ester
• 4-Hydroxy-1-piperidinecarboxylic acid tert-butyl ester
• 4-Hydroxy-N-(tert-butoxycarbonyl)piperidine
• 4-Hydroxy-N-Boc-piperidine
• 4-Hydroxy-Piperidine-1-Carboxylic Acid Tert-Butyl Ester
• 4-Hydroxypiperidine-1-carboxylic acid tert-butyl ester
• Boc-(4-Hydroxy)-Piperidine
• N-(Tert-Butoxycarbonyl)-4-Hydroxypiperidine
• N-(Tert-Butoxycarbonyl)-4-Piperidinol
• N-(tert-Butoxycarbonyl)piperidin-4-ol
• N-(tert-Butyloxycarbonyl)-4-hydroxypiperidine
• N-(tert-Butyloxycarbonyl)-4-piperidinol
• N-Boc-4-Hydroxylpiperidine
• N-Boc-4-Hydroxypiperidine
• N-Boc-4-hydropiperidine
• N-Boc-4-hydroxy-1-piperidine
• Tert-Butyl 4-Hydroxy-1-Piperidinecarboxylate
• Tert-Butyl 4-Hydroxypiperidine-1-Carboxylate
• tert-Butyl 4-hydroxylpiperidine-1-carboxylate

1-(tert-Butoxycarbonyl)-4-hydroxypiperidine

CAS: 109384-19-2

Formula: C₁₀H₁₉NO₃

Purity: >97.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 201.27

Ref: 3B-B2671

1-Boc-4-hydroxypiperidine, 98%

CAS: 109384-19-2

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₉NO₃

Purity: 98%

Color and Shape: White, Powder

Molecular weight: 201.27

Ref: 02-L19275

4-Hydroxypiperidine, N-BOC protected

CAS: 109384-19-2

4-Hydroxypiperidine, N-BOC protected

Formula: C₁₀H₁₉NO₃

Purity: 98%

Color and Shape: white powder

Molecular weight: 201.26g/mol

Ref: 54-OR5404

4-Hydroxypiperidine-3,3,4,5,5-d5-N-t-BOC(Hydroxypiperidine-c

CAS: 109384-19-2, 1523606-18-9

Purity: 98 atom % D

Molecular weight: 206.30

Ref: 3U-D7793

1-tert-Butoxycarbonyl-4-hydroxypiperidine

CAS: 109384-19-2

Formula: C₁₀H₁₉NO₃

Purity: 98%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 201.266

Ref: 10-F008952

N-Boc-4-Hydroxypiperidine

Controlled Product

CAS: 109384-19-2

Applications N-Boc-4-hydroxypiperidine is a 4-hydroxypyridine with a boc protecting group used in the preparation of neurologically active agents and other pharmaceutical compounds.
References Kwon, Y.E. et al.: Bioorg. Med. Chem., 15, 6596 (2007); Knutsen, L.J.S. et al.: J. Med. Chem., 42, 3463 (1999);

Formula: C₁₀H₁₉NO₃

Color and Shape: Neat

Molecular weight: 201.26

Ref: TR-B656660

1-Boc-4-piperidinol

CAS: 109384-19-2

1-Boc-4-piperidinol is an inhibitor of serine proteases. It also has potent inhibitory activity against 5-HT2A receptors and inhibits the growth of cancer cells. 1-Boc-4-piperidinol is a molecule that contains a hydroxy group and a serine protease inhibitor. It reacts with hydrochloric acid to form 1-boc piperazine, which is then reacted with hydrogen chloride to form the final product. The pharmacokinetic properties of this drug are not known due to the lack of oral bioavailability in rats. However, it does show slow absorption by inhalation and subcutaneous administration, suggesting that it may be absorbed through these routes as well.

Formula: C₁₀H₁₉NO₃

Purity: Min. 95%

Color and Shape: Off-White Powder

Molecular weight: 201.26 g/mol

Ref: 3D-FB11285

N-BOC-4-Hydroxypiperidine

CAS: 109384-19-2

Formula: C₁₀H₁₉NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 201.2628

Ref: IN-DA0037YP