CAS 1093861-60-9
:Afoxolaner
Description:
Afoxolaner is an insecticide and acaricide belonging to the isoxazoline class of compounds, primarily used in veterinary medicine for the treatment and prevention of flea and tick infestations in dogs and cats. Its mechanism of action involves the inhibition of gamma-aminobutyric acid (GABA) and glutamate-gated chloride channels, leading to paralysis and death of the target parasites. Afoxolaner is characterized by its high efficacy against a broad spectrum of ectoparasites, including fleas, ticks, and mites, and is typically administered orally in the form of chewable tablets. The compound is known for its long-lasting effects, providing protection for several weeks after administration. Afoxolaner is generally well-tolerated in pets, with a low incidence of adverse effects. Its safety profile, combined with its effectiveness, has made it a popular choice among veterinarians for managing parasitic infestations. As with any pharmaceutical, it is important to follow dosage guidelines and consult a veterinarian for appropriate use.
Formula:C26H17ClF9N3O3
InChI:InChI=1S/C26H17ClF9N3O3/c27-15-8-13(7-14(9-15)25(31,32)33)23(26(34,35)36)10-20(39-42-23)18-5-6-19(17-4-2-1-3-16(17)18)22(41)37-11-21(40)38-12-24(28,29)30/h1-9H,10-12H2,(H,37,41)(H,38,40)
InChI key:InChIKey=OXDDDHGGRFRLEE-UHFFFAOYSA-N
SMILES:C(F)(F)(F)C1(CC(=NO1)C=2C3=C(C(C(NCC(NCC(F)(F)F)=O)=O)=CC2)C=CC=C3)C4=CC(C(F)(F)F)=CC(Cl)=C4
Synonyms:- 4-[5-(3-chloro-5-trifluoromethylphenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-naphthalene-1-carboxylic acid [(2,2,2-trifluoroethylcarbamoyl)-methyl]-amide
- 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-
- 1-Naphthalenecarboxamide, 4-[5-[3-chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-
- 4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide
- Afoxolaner
- Nexgard
- Avrana
- China biggest manufacturer,Afoxolaner,1093861-60-9
- 4-(5-(3-Chloro-5-(trifluoromethyl)phenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-N-(2-oxo-2-((2,2,2-trifluoroethyl)amino)ethyl)-1-naphthamide
- afoxolaner-007
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 12 products.
4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2-[(2,2,2-trifluoroethyl)amino]ethyl]-1-naphthalenecarboxamide
CAS:Formula:C26H17ClF9N3O3Purity:98%Color and Shape:SolidMolecular weight:625.8701Afoxolaner
CAS:<p>Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs.</p>Formula:C26H17ClF9N3O3Purity:99.1% - 99.38%Color and Shape:SolidMolecular weight:625.87Afoxolaner (Standard)
CAS:Afoxolaner (Standard) is the standard substance of Afoxolaner, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Afoxolaner is an isoxazoline insecticide/acaricide against Ixodes scapularis in dogs. Afoxolaner acts on the insect GABA and glutamate receptors, inhibiting GABA & glutamate-regulated uptake of chloride ions, resulting in excess neuronal stimulation and death of the arthropod.Formula:C26H17ClF9N3O3Molecular weight:625.87Afoxolaner 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C26H17ClF9N3O3Color and Shape:Single SolutionMolecular weight:625.87Afoxolaner
CAS:Afoxolaner is a bicyclic heterocycle that belongs to the class of insecticides. It is administered orally and has a high bioavailability in rats and dogs. Afoxolaner has been shown to have a pharmacokinetic profile similar to that of the reference drug, deltamethrin, with an effective dose range from 0.1-0.5 mg/kg in rats and dogs. The terminal half-life of afoxolaner is 7 days after oral administration. Afoxolaner is also effective against fleas, ticks, lice, mites, and mosquitoes in animal models and has been shown to be safe for use in cats and dogs at doses up to 1mg/kg (1mg/kg). There are no reports of allergic reactions or cutaneous lesions related to afoxolaner treatment.Formula:C26H17ClF9N3O3Purity:Min. 95%Color and Shape:PowderMolecular weight:625.87 g/mol
![4-[5-[3-Chloro-5-(trifluoromethyl)phenyl]-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]-N-[2-oxo-2…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0096RY.jpg&w=3840&q=75)
