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CAS 109389-30-2

:

deoxyuridine-ce phosphoramidite*for cyclone

Description:
Deoxyuridine-5'-ce phosphoramidite, with the CAS number 109389-30-2, is a chemical compound commonly used in the field of molecular biology, particularly in the synthesis of oligonucleotides. This compound is a derivative of deoxyuridine, which is a nucleoside that forms part of DNA. The "phosphoramidite" designation indicates that it contains a phosphoramidite group, which is crucial for the stepwise synthesis of DNA strands through solid-phase synthesis techniques. The presence of the "ce" (cyclic ether) suggests modifications that may enhance the stability or reactivity of the compound during synthesis. Deoxyuridine-5'-ce phosphoramidite is typically utilized in the construction of DNA sequences for various applications, including genetic research, therapeutic development, and diagnostics. Its characteristics include a relatively high reactivity in coupling reactions, allowing for efficient incorporation into growing oligonucleotide chains. Additionally, it is often stored under anhydrous conditions to prevent hydrolysis, which can compromise its efficacy in synthesis.
Formula:C39H47N4O8P
InChI:InChI=1S/C39H47N4O8P/c1-27(2)43(28(3)4)52(49-24-10-22-40)51-34-25-37(42-23-21-36(44)41-38(42)45)50-35(34)26-48-39(29-11-8-7-9-12-29,30-13-17-32(46-5)18-14-30)31-15-19-33(47-6)20-16-31/h7-9,11-21,23,27-28,34-35,37H,10,24-26H2,1-6H3,(H,41,44,45)/t34-,35+,37+,52?/m0/s1
InChI key:InChIKey=ZGJUDTLSWZPIDW-MVFNBKNKSA-N
SMILES:C(OC[C@@H]1[C@@H](OP(N(C(C)C)C(C)C)OCCC#N)C[C@@H](O1)N2C(=O)NC(=O)C=C2)(C3=CC=C(OC)C=C3)(C4=CC=C(OC)C=C4)C5=CC=CC=C5
Synonyms:
  • 5'-O-DMT-2'-deoxyuridine-3'-CE-Phosphoramidite
  • 5′-O-(4,4′-Dimethoxytrityl)-2′-deoxyuridine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
  • Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
  • Uridine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxy-, 3′-[2-cyanoethyl bis(1-methylethyl)phosphoramidite]
  • N-blocked-5'-O-DMT 3'-CED deoxyuridine phosphoramidite
  • 5'-O-(4, 4'-Dimethoxytrityl)-2'-deoxyuridine-3'-CE-Phosphoramidite
  • deoxyuridine-ce phosphoramidite*for cyclone
  • 5'-DMT-dU phosphoramidite
  • DMT-DU AMIDITE 0.25G 89 SINGLE
  • DMT-DURIDINE CYANOETHYL PHOSPHORAMIDITE)
  • See more synonyms
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