CAS 1093978-89-2

2H-1-Benzazepin-2-one,6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-

Description:

2H-1-Benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-, identified by CAS number 1093978-89-2, is a complex organic compound characterized by its multi-cyclic structure, which includes a benzazepine core fused with a triazole and imidazole moiety. The presence of a fluorine atom and a trifluoroethyl group suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals with enhanced biological activity or selectivity. The methoxy and methyl substituents may influence the compound's solubility and lipophilicity, affecting its pharmacokinetic properties. Additionally, the intricate arrangement of functional groups indicates potential for diverse interactions with biological targets, making it a candidate for further investigation in drug discovery. Overall, this compound exemplifies the complexity often found in modern synthetic organic chemistry, particularly in the context of designing molecules for therapeutic use.

Formula: C₂₅H₂₂F₄N₆O₂

Synonyms:

• 6-fluoro-3-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]-1-(2,2,2-trifluoroethyl)-4,5-dihydro-3H-1-benzazepin-2-one
• 2H-1-benzazepin-2-one, 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 2H-1-Benzazepin-2-one 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-one
• gaMMa-secretase Modulator 2
• 6-fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-Benzazepin-2-on
• Merck gamma-secretase modulator
• gamma secretase modulator 2,gammasecretase modulator 2
• 6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-Methoxy-4-(4-Methyl-1H-iMidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-
• Merck γ-secretase Modulator

6-Fluoro-1,3,4 ,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1 ,2,3-triazol-1-yl]-1-(2-trifluoroethyl)-2H-1-benzazepin-2-one

CAS: 1093978-89-2

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-- 1,2,3-triazol-1yl]-1-(2trifluoroethyl)-2H-1benzazepin-2one (6FTH) is an anticancer drug that belongs to the class of benzothiazole derivatives. It has been shown to have potent antiangiogenic and antiproliferative properties in preclinical studies. 6FTH has been shown to be effective against colon cancer and breast cancer cells in vitro. It also inhibits the growth of squamous cell carcinoma cells by downregulating the expression of proteins involved in tumorigenesis. The compound has been found to be safe when used as an adjuvant to a combination therapy containing cisplatin

Formula: C₂₅H₂₂F₄N₆O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 514.48 g/mol

Ref: 3D-FB151723

6-Fluoro-1,3,4,5-tetrahydro-3-[4-[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]-1H-1,2,3-triazol-1-yl]-1-(2,2,2-trifluoroethyl)-2H-1-benzazepin-2-one

Controlled Product

CAS: 1093978-89-2

Formula: C₂₅H₂₂F₄N₆O₂

Color and Shape: Neat

Molecular weight: 514.475

Ref: TR-F257310

γ-secretase modulator 2

CAS: 1093978-89-2

Gamma-secretase modulator 2 selectively targets Alzheimer's by reducing Aβ(1-42), aiding in prevention and treatment.

Formula: C₂₅H₂₂F₄N₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 514.47

Ref: TM-T11359