12(R)-HEPE, or 12(R)-hydroxyeicosapentaenoic acid, is a bioactive lipid derived from eicosapentaenoic acid (EPA), an omega-3 fatty acid. This compound is characterized by its hydroxyl group at the 12th carbon position, which contributes to its unique biological activities. 12(R)-HEPE is known for its anti-inflammatory properties and plays a role in various physiological processes, including modulation of immune responses and promotion of resolution of inflammation. It is involved in the synthesis of specialized pro-resolving mediators, which are crucial for the resolution phase of inflammation. The compound has garnered interest in research related to cardiovascular health, neuroprotection, and metabolic disorders. Its potential therapeutic applications are being explored, particularly in the context of chronic inflammatory diseases. As a naturally occurring substance, 12(R)-HEPE is typically found in marine sources and can be synthesized through enzymatic pathways in the body. Its stability and reactivity are influenced by the presence of the hydroxyl group, making it a subject of interest in both nutritional and pharmaceutical research.

12(R)-HEPE

109430-12-8: 12(R)-HEPE, or 12(R)-hydroxyeicosapentaenoic acid, is a bioactive lipid derived from eicosapentaenoic acid (EPA), an omega-3 fatty acid. This compound is characterized by its hydroxyl group at the 12th carbon position, which contributes to its unique biological activities. 12(R)-HEPE is known for its anti-inflammatory properties and plays a role in various physiological processes, including modulation of immune responses and promotion of resolution of inflammation. It is involved in the synthesis of specialized pro-resolving mediators, which are crucial for the resolution phase of inflammation. The compound has garnered interest in research related to cardiovascular health, neuroprotection, and metabolic disorders. Its potential therapeutic applications are being explored, particularly in the context of chronic inflammatory diseases. As a naturally occurring substance, 12(R)-HEPE is typically found in marine sources and can be synthesized through enzymatic pathways in the body. Its stability and reactivity are influenced by the presence of the hydroxyl group, making it a subject of interest in both nutritional and pharmaceutical research.

12(R)-hydroxy-5(Z),8(Z),10(E),14(Z),17(Z)-eicosapentaenoic acid

<p>12(R)-HEPE, a monohydroxy fatty acid derived from EPA in the eggs of the sea urchin S. purpuratus, has a biological activity that, while not extensively documented, may resemble that of 12(R)-HETE (Catalog No.34560).</p>

CAS 109430-12-8

12(R)-HEPE

12(R)-hydroxy-5(Z),8(Z),10(E),14(Z),17(Z)-eicosapentaenoic acid

Ref: 48-14-2096

12(R)-HEPE

Ref: TM-T84563