CAS 109481-23-4

5-Oxo-L-prolyl-L-glutamine

Description:

5-Oxo-L-prolyl-L-glutamine, with the CAS number 109481-23-4, is a dipeptide derivative that features a unique combination of amino acid residues. This compound is characterized by the presence of a proline and glutamine moiety, linked through a peptide bond, with an additional oxo group at the 5-position of the proline. The structure contributes to its potential biological activity, particularly in the context of protein synthesis and cellular signaling. It is soluble in water, which is typical for many peptides, and may exhibit specific interactions with biological receptors or enzymes due to its structural features. The compound's stability, reactivity, and potential applications in pharmaceuticals or biochemistry are influenced by its amino acid composition and the presence of the oxo group. As with many peptides, its properties can be affected by factors such as pH, temperature, and the presence of other ions or molecules in solution. Further research may elucidate its specific roles in biological systems or therapeutic applications.

Formula: C₁₀H₁₅N₃O₅

InChI: InChI=1S/C10H15N3O5/c11-7(14)3-1-6(10(17)18)13-9(16)5-2-4-8(15)12-5/h5-6H,1-4H2,(H2,11,14)(H,12,15)(H,13,16)(H,17,18)/t5-,6-/m0/s1

InChI key: InChIKey=ILAITOFTZJRIFJ-WDSKDSINSA-N

SMILES: C(N[C@@H](CCC(N)=O)C(O)=O)(=O)[C@H]1NC(=O)CC1

Synonyms:

• L-Glutamine, 5-oxo-L-prolyl-
• L-Glutamine, N2-(5-oxo-L-prolyl)-
• 5-Oxo-L-prolyl-L-glutamine
• Glutamine, N2-L-pyroglutamyl-, L-

Pyr-Gln-OH

CAS: 109481-23-4

Pyr-Gln-OH is an intermediate in the synthesis of didemnin, a molecule that has been shown to inhibit cancer cell growth. Pyr-Gln-OH is also involved in the production of histamine, which is a neurotransmitter that plays a role in many bodily functions. Pyr-Gln-OH may be used as a diagnostic agent for bladder cancer. Excretion of this molecule was found to be increased in patients with bladder cancer and decreased in those without the disease. Biochemical profiling revealed that Pyr-Gln-OH is elevated in patients with bladder cancer and lower levels are found in healthy individuals.

Formula: C₁₀H₁₅N₃O₅

Purity: Min. 95%

Molecular weight: 257.24 g/mol

Ref: 3D-FP108286

Pyr-Gln-OH

Controlled Product

CAS: 109481-23-4

Applications Pyr-Gln-OHis a dipeptide that is found in fruits, has a role as a human metabolite.
References Dallmann, Robert. et al., P. NATL. ACAD. SCI. USA. 109, 2625-2629(2012);

Formula: C₁₀H₁₅N₃O₅

Color and Shape: Neat

Molecular weight: 257.243

Ref: TR-P840733

Pyr-Gln-OH trifluoroacetate

CAS: 109481-23-4

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Formula: C₁₀H₁₅N₃O₅•(C₂HF₃O₂)x

Purity: Min. 95%

Ref: 3D-FP183378