CAS 1095-90-5
:Methadone hydrochloride
Description:
Methadone hydrochloride is a synthetic opioid used primarily in the treatment of opioid addiction and for pain management. It is a white to off-white crystalline powder that is soluble in water and alcohol, which facilitates its administration in various forms, including oral and injectable routes. The substance acts as a long-acting agonist at the mu-opioid receptors in the central nervous system, providing analgesic effects while also helping to mitigate withdrawal symptoms in individuals dependent on other opioids. Methadone has a relatively long half-life, allowing for once-daily dosing in maintenance therapy. Its pharmacokinetics can be influenced by factors such as metabolism, age, and concurrent medications, necessitating careful monitoring to avoid potential toxicity or overdose. Additionally, methadone can cause side effects typical of opioids, including respiratory depression, sedation, and constipation. Due to its potential for abuse and dependence, methadone is classified as a controlled substance in many jurisdictions, and its use is typically regulated within specialized treatment programs.
Formula:C21H27NO·ClH
InChI:InChI=1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H
InChI key:InChIKey=FJQXCDYVZAHXNS-UHFFFAOYSA-N
SMILES:C(CC(N(C)C)C)(C(CC)=O)(C1=CC=CC=C1)C2=CC=CC=C2.Cl
Synonyms:- (±)-Methodone hydrochloride
- 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride
- 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride (1:1)
- 4,4-Diphenyl-6-dimethylamino-3-heptanone hydrochloride
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Dihydrochloride
- 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Hydrochloride (1:1)
- 6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
- <span class="text-smallcaps">D</smallcap>,<smallcap>L</span>-Methadone hydrochloride
- <span class="text-smallcaps">DL</span>-Methadone hydrochloride
- Adanon
- Adanon hydrochloride
- Adolan
- Algidon
- Algolysin
- Amidon
- An 148
- Butalgin
- Depridol
- Diaminon hydrochloride
- Dolofin hydrochloride
- Dolophin hydrochloride
- Dolophine
- Fenadon
- Fenadone
- Heptadon
- Hoechst 10820
- Ketalgin
- Ketalgin hydrochloride
- Mecodin
- Mephenon
- Methadone HCl
- Methadone Hydrochloride {D.D.}
- Methadose
- Miadone
- Moheptan
- NSC 19600
- Phenadone hydrochloride
- Polamidon
- Racemic methadone hydrochloride
- dl-6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
- dl-Methadone hydrochloride
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 10 products.
d,l-Methadone.HCl, 1mg/ml in Methanol (as free base)
CAS:Controlled ProductColor and Shape:Single Solutionrac Methadone Hydrochloride
CAS:Controlled Product<p>Applications Controlled substance (opiate). Used in treatment of opioid dependence.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bishara, R.H., et al.: Anal. Profiles Drug Subs., 3, 365 (1974), Senay, E.C., et al.: Int. J. Addict., 20, 803 (1985), Inturrisi, C.E., et al.: Clin. Pharmacol. Ther., 41, 392 (1987), Sees, K.L., et al.: J. Am. Med. Assoc., 283, 1303 (2000),<br></p>Formula:C21H27NO·ClHColor and Shape:WhiteMolecular weight:345.91Methadone hydrochloride
CAS:Controlled ProductMethadone hydrochlorideFormula:C21H27NOHClPurity:99.9%Color and Shape:WhiteMolecular weight:345.18594rac Methadone Hydrochloride (1 mg/mL in Methanol)
CAS:Controlled ProductFormula:C21H27NO·ClHColor and Shape:Single SolutionMolecular weight:345.91Methadone Hydrochloride CII
CAS:Controlled Product<p>Amfepramone (inn), methadone (inn), and normethadone (i</p>Formula:C21H27NO·HClColor and Shape:White Crystalline PowderMolecular weight:309.20926rac Methadone hydrochloride
CAS:Controlled Product<p>Methadone is an opioid and narcotic analgesic. It binds to the opioid receptors in the brain, spinal cord, and other organs, reducing pain by blocking the transmission of pain signals. Methadone is used medically as a painkiller and as a treatment for opiate addiction. The drug may also be used to treat chronic pain not caused by cancer or other diseases that are resistant to treatment with other medications. Methadone is usually administered orally but can also be given intravenously or intramuscularly. Methadone hydrochloride is a long-acting form of methadone that is taken orally and has a half-life of approximately 24 hours. This medication has been shown to have serotonergic activity, which could lead to life-threatening reactions such as serotonin syndrome when it interacts with certain drugs such as antidepressants, antipsychotics, or nonsteroidal anti-inflammatory drugs (NSAIDs). Methadone hydrochloride has been shown to affect cardiac function through</p>Formula:C21H27NO•HClPurity:Min. 95%Color and Shape:PowderMolecular weight:345.91 g/mol
