CAS 1095-90-5

Methadone hydrochloride

Description:

Methadone hydrochloride is a synthetic opioid used primarily in the treatment of opioid addiction and for pain management. It is a white to off-white crystalline powder that is soluble in water and alcohol, which facilitates its administration in various forms, including oral and injectable routes. The substance acts as a long-acting agonist at the mu-opioid receptors in the central nervous system, providing analgesic effects while also helping to mitigate withdrawal symptoms in individuals dependent on other opioids. Methadone has a relatively long half-life, allowing for once-daily dosing in maintenance therapy. Its pharmacokinetics can be influenced by factors such as metabolism, age, and concurrent medications, necessitating careful monitoring to avoid potential toxicity or overdose. Additionally, methadone can cause side effects typical of opioids, including respiratory depression, sedation, and constipation. Due to its potential for abuse and dependence, methadone is classified as a controlled substance in many jurisdictions, and its use is typically regulated within specialized treatment programs.

Formula: C₂₁H₂₇NO·ClH

InChI: InChI=1S/C21H27NO.ClH/c1-5-20(23)21(16-17(2)22(3)4,18-12-8-6-9-13-18)19-14-10-7-11-15-19;/h6-15,17H,5,16H2,1-4H3;1H

InChI key: InChIKey=FJQXCDYVZAHXNS-UHFFFAOYSA-N

SMILES: C(CC(N(C)C)C)(C(CC)=O)(C1=CC=CC=C1)C2=CC=CC=C2.Cl

Synonyms:

• (±)-Methodone hydrochloride
• 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride
• 3-Heptanone, 6-(dimethylamino)-4,4-diphenyl-, hydrochloride (1:1)
• 4,4-Diphenyl-6-dimethylamino-3-heptanone hydrochloride
• 6-(Dimethylamino)-4,4-Diphenylheptan-3-One
• 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Dihydrochloride
• 6-(Dimethylamino)-4,4-Diphenylheptan-3-One Hydrochloride (1:1)
• 6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
• <span class="text-smallcaps">D</smallcap>,<smallcap>L</span>-Methadone hydrochloride
• <span class="text-smallcaps">DL</span>-Methadone hydrochloride
• Adanon
• Adanon hydrochloride
• Adolan
• Algidon
• Algolysin
• Amidon
• An 148
• Butalgin
• Depridol
• Diaminon hydrochloride
• Dolofin hydrochloride
• Dolophin hydrochloride
• Dolophine
• Fenadon
• Fenadone
• Heptadon
• Hoechst 10820
• Ketalgin
• Ketalgin hydrochloride
• Mecodin
• Mephenon
• Methadone HCl
• Methadone Hydrochloride {D.D.}
• Methadose
• Miadone
• Moheptan
• NSC 19600
• Phenadone hydrochloride
• Polamidon
• Racemic methadone hydrochloride
• dl-6-Dimethylamino-4,4-diphenyl-3-heptanone hydrochloride
• dl-Methadone hydrochloride

d,l-Methadone.HCl

Controlled Product

CAS: 1095-90-5

Color and Shape: Neat

Ref: LP-MET-637-HC-10

d,l-Methadone.HCl, 1mg/ml in Methanol (as free base)

Controlled Product

CAS: 1095-90-5

Color and Shape: Single Solution

Ref: LP-MET-637-HC-1LM

Methadone Hydrochloride

Controlled Product

CAS: 1095-90-5

Color and Shape: Neat

Ref: 61-FOR0531.00

Methadone Hydrochloride

Controlled Product

CAS: 1095-90-5

Color and Shape: white solid

Ref: 61-LGCFOR0531.00

Methadone Hydrochloride

Controlled Product

CAS: 1095-90-5

Color and Shape: Neat

Ref: 86-MM0531.00

rac Methadone Hydrochloride

Controlled Product

CAS: 1095-90-5

Applications Controlled substance (opiate). Used in treatment of opioid dependence.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Bishara, R.H., et al.: Anal. Profiles Drug Subs., 3, 365 (1974), Senay, E.C., et al.: Int. J. Addict., 20, 803 (1985), Inturrisi, C.E., et al.: Clin. Pharmacol. Ther., 41, 392 (1987), Sees, K.L., et al.: J. Am. Med. Assoc., 283, 1303 (2000),

Formula: C₂₁H₂₇NO·ClH

Color and Shape: White

Molecular weight: 345.91

Ref: TR-M225865

Methadone hydrochloride

Controlled Product

CAS: 1095-90-5

Methadone hydrochloride

Formula: C₂₁H₂₇NOHCl

Purity: 99.9%

Color and Shape: White

Molecular weight: 345.18594

Ref: 47-552

rac Methadone Hydrochloride (1 mg/mL in Methanol)

Controlled Product

CAS: 1095-90-5

Formula: C₂₁H₂₇NO·ClH

Color and Shape: Single Solution

Molecular weight: 345.91

Ref: TR-KIT0090

Methadone Hydrochloride CII

Controlled Product

CAS: 1095-90-5

Amfepramone (inn), methadone (inn), and normethadone (i

Formula: C₂₁H₂₇NO·HCl

Color and Shape: White Crystalline Powder

Molecular weight: 309.20926

Ref: 45-1398009

rac Methadone hydrochloride

Controlled Product

CAS: 1095-90-5

Methadone is an opioid and narcotic analgesic. It binds to the opioid receptors in the brain, spinal cord, and other organs, reducing pain by blocking the transmission of pain signals. Methadone is used medically as a painkiller and as a treatment for opiate addiction. The drug may also be used to treat chronic pain not caused by cancer or other diseases that are resistant to treatment with other medications. Methadone is usually administered orally but can also be given intravenously or intramuscularly. Methadone hydrochloride is a long-acting form of methadone that is taken orally and has a half-life of approximately 24 hours. This medication has been shown to have serotonergic activity, which could lead to life-threatening reactions such as serotonin syndrome when it interacts with certain drugs such as antidepressants, antipsychotics, or nonsteroidal anti-inflammatory drugs (NSAIDs). Methadone hydrochloride has been shown to affect cardiac function through

Formula: C₂₁H₂₇NO•HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 345.91 g/mol

Ref: 3D-FR27536