CAS: 1095173-27-5 - N-[(2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N′-(4-cyanophenyl)urea

Formula: C₂₁H₂₂N₆O

InChI: InChI=1S/C21H22N6O/c1-27-11-10-16(24-21(28)23-15-8-6-14(13-22)7-9-15)12-19(27)20-25-17-4-2-3-5-18(17)26-20/h2-9,16,19H,10-12H2,1H3,(H,25,26)(H2,23,24,28)/t16-,19-/m1/s1

InChI key: InChIKey=SFNSLLSYNZWZQG-VQIMIIECSA-N

SMILES: N#CC1=CC=C(C=C1)NC(=O)NC2CCN(C)C(C3=NC=4C=CC=CC4N3)C2

Synonyms:

• Glasdegib
• N-[(2R,4R)-2-(1H-Benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N′-(4-cyanophenyl)urea
• Urea, N-[(2R,4R)-2-(1H-benzimidazol-2-yl)-1-methyl-4-piperidinyl]-N′-(4-cyanophenyl)-
• PF 04449913

Glasdegib

CAS: 1095173-27-5

• Formula: C₂₁H₂₂N₆O
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 374.44

Glasdegib

CAS: 1095173-27-5

Glasdegib (PF-04449913) (PF-04449913) is a potent, and orally bioavailable Smoothened (Smo) inhibitor with IC50 of …

• Formula: C₂₁H₂₂N₆O
• Purity: 98.00%
• Color and Shape: Solid
• Molecular weight: 374.44

PF 04449913

CAS: 1095173-27-5

PF 04449913 is a potent inhibitor of the enzyme caspase-3. It has been shown to …

• Formula: C₂₁H₂₂N₆O
• Purity: Min. 95%
• Molecular weight: 374.45 g/mol

PF 04449913

CAS: 1095173-27-5

• Formula: C₂₁H₂₂N₆O
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 374.4390

Glasdegib

CAS: 1095173-27-5

Applications Glasdegib acts as a potent, orally biovailablesmoothened (Smo) inhibitor used in the treatment of …

• Formula: C₂₁H₂₂N₆O
• Color and Shape: Off-White Solid
• Molecular weight: 374.44