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CAS 109539-58-4

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leucinostatin H

Description:
Leucinostatin H is a naturally occurring compound classified as a peptide antibiotic, primarily known for its antimicrobial properties. It is produced by certain strains of the bacterium Streptomyces, which are renowned for their ability to synthesize a wide variety of bioactive compounds. Leucinostatin H exhibits a complex structure characterized by a cyclic arrangement of amino acids, which contributes to its stability and biological activity. This compound has been studied for its potential applications in medicine, particularly in the development of new antibiotics to combat resistant bacterial strains. Its mechanism of action typically involves inhibition of protein synthesis in target organisms, making it effective against a range of pathogens. Additionally, leucinostatin H may possess immunomodulatory effects, further enhancing its therapeutic potential. As with many peptide antibiotics, research continues to explore its full range of biological activities and possible applications in clinical settings.
Formula:C57H103N11O12
InChI:InChI=1/C57H103N11O12/c1-19-36(10)22-23-44(70)68-31-37(11)30-42(68)50(75)62-39(27-32(2)3)48(73)64-45(46(71)35(8)9)51(76)66-56(15,16)53(78)63-40(28-33(4)5)47(72)61-41(29-34(6)7)49(74)65-57(17,18)54(79)67-55(13,14)52(77)59-25-24-43(69)60-38(12)21-20-26-80-58/h22-23,32-42,45-46,71H,19-21,24-31,58H2,1-18H3,(H,59,77)(H,60,69)(H,61,72)(H,62,75)(H,63,78)(H,64,73)(H,65,74)(H,66,76)(H,67,79)/b23-22+/t36-,37?,38?,39?,40?,41?,42?,45?,46?/m1/s1
Synonyms:
  • N-[1-[[1-[[2-[[1-[[1-[[2-[[2-[[3-[(4-aminooxy-1-methyl-butyl)amino]-3-oxo-propyl]amino]-1,1-dimethyl-2-oxo-ethyl]amino]-1,1-dimethyl-2-oxo-ethyl]carbamoyl]-3-methyl-butyl]carbamoyl]-3-methyl-butyl]amino]-1,1-dimethyl-2-oxo-ethyl]carbamoyl]-2-hydroxy-3-methyl-butyl]carbamoyl]-3-methyl-butyl]-4-methyl-1-[(E,4R)-4-methylhex-2-enoyl]pyrrolidine-2-carboxamide
  • Leucinostatin H
  • Paecilotoxin H
  • Leucinostatin A, 2-L-leucine, N9-oxide
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