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CAS 109552-15-0

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Disodium pamidronate pentahydrate

Description:
Disodium pamidronate pentahydrate is a bisphosphonate compound primarily used in the treatment of bone disorders, such as osteoporosis and Paget's disease, as well as in managing hypercalcemia associated with malignancies. Its chemical formula reflects the presence of two sodium ions and a pentahydrate, indicating that it contains five water molecules per formula unit. This compound acts by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain bone density and strength. Disodium pamidronate is typically administered intravenously and is known for its relatively low toxicity profile compared to other treatments. In terms of physical properties, it is usually presented as a white to off-white crystalline powder, which is soluble in water but insoluble in organic solvents. The stability of the compound is influenced by factors such as pH and temperature, making proper storage conditions essential for maintaining its efficacy. Overall, disodium pamidronate pentahydrate plays a significant role in managing various bone-related conditions through its action on bone metabolism.
Formula:C3H11NO7P2·5H2O·2Na
InChI:InChI=1S/C3H11NO7P2.2Na.5H2O/c4-2-1-3(5,12(6,7)8)13(9,10)11;;;;;;;/h5H,1-2,4H2,(H2,6,7,8)(H2,9,10,11);;;5*1H2
InChI key:InChIKey=LOQDXDBJGWSFHH-UHFFFAOYSA-N
SMILES:C(P(=O)(O)O)(P(=O)(O)O)(CCN)O.[Na].O
Synonyms:
  • 3-Amino-1-Hydroxy-1-Phosphonopropyl Phosphonic Acid Disodium Salt
  • Disodium (3-Amino-1-Hydroxypropane-1,1-Diyl)Bis[Hydrogen (Phosphonate)]
  • Disodium pamidronate pentahydrate
  • Pamidronate Disodium
  • Pamidronate Disodium Salt
  • Phosphonic acid, (3-amino-1-hydroxypropylidene)bis-, disodium salt, pentahydrate
  • Phosphonic acid, P,P′-(3-amino-1-hydroxypropylidene)bis-, sodium salt, hydrate (1:2:5)
  • phosphonate, P,P'-(3-amino-1-hydroxypropylidene)bis-, sodium salt (1:2)
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