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CAS 1096-80-6

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2,3,5-Triphenyltetrazolium bromide

Description:
2,3,5-Triphenyltetrazolium bromide (TTC) is a chemical compound commonly used as a redox indicator in biological and biochemical assays. It is a tetrazolium salt that is typically utilized to assess cell viability and metabolic activity, as living cells can reduce TTC to form a red-colored formazan product. This compound is characterized by its stability, solubility in water, and ability to undergo reduction in the presence of viable cells. The presence of three phenyl groups contributes to its hydrophobic characteristics, while the tetrazolium ring is crucial for its redox properties. TTC is often employed in microbiological studies, cytotoxicity assays, and as a histological stain. Its use is particularly valuable in distinguishing between living and dead cells, as only metabolically active cells can convert TTC into its formazan derivative. Safety precautions should be taken when handling TTC, as with many chemical substances, to avoid potential health hazards.
Formula:C19H15BrN4
InChI:InChI=1/C19H16N4.BrH/c1-4-10-16(11-5-1)19-20-22(17-12-6-2-7-13-17)23(21-19)18-14-8-3-9-15-18;/h1-15H,(H,20,21);1H
InChI key:InChIKey=YZSUTKMFUHJPNB-UHFFFAOYSA-M
SMILES:N1([N+](=NC(=N1)C2=CC=CC=C2)C3=CC=CC=C3)C4=CC=CC=C4.[Br-]
Synonyms:
  • 2,3,5-Triphenyl-2H-tetrazolium bromide
  • 2,3,5-triphenyl-2,3-dihydro-1H-tetrazol-3-ium bromide
  • 2,3,5-triphenyl-2H-tetrazol-3-ium
  • 2,3,5-triphenyl-2H-tetrazol-3-ium bromide
  • 2H-Tetrazolium, 2,3,5-triphenyl-, bromide
  • 2H-Tetrazolium, 2,3,5-triphenyl-, bromide (1:1)
  • Ai3-62388
  • Tetrazolium, 2,3,5-triphenyl-2H-, bromide
  • Triphenyltetrazolium bromide
  • 2,3,5-Triphenyltetrazolium bromide
  • See more synonyms
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