CAS 1096144-06-7

1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-

Description:

1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, with CAS number 1096144-06-7, is a complex organophosphorus compound characterized by its unique oxaphosphorinan ring structure. This compound features a phosphorus atom bonded to an oxygen atom, contributing to its reactivity and potential applications in various chemical processes. The presence of multiple phenylmethoxy groups enhances its solubility and stability, making it suitable for use in organic synthesis and potentially in pharmaceutical applications. The stereochemistry indicated by the (2S,3S,4S,5S,6R) configuration suggests specific spatial arrangements of its substituents, which can influence its biological activity and interaction with other molecules. Additionally, the compound's properties, such as melting point, boiling point, and solubility, would depend on its molecular interactions and the presence of functional groups. Overall, this compound represents a fascinating area of study within organophosphorus chemistry, with implications for both industrial and research applications.

Formula: C₃₂H₃₃O₆P

Synonyms:

• PST3 1a (NSC-753859)
• 1,2-Oxaphosphorinan-3-ol, 2-phenyl-4,5-bis(phenylmethoxy)-6-[(phenylmethoxy)methyl]-, 2-oxide, (2S,3S,4S,5S,6R)-

PST3.1a

CAS: 1096144-06-7

PST3.1a is a selective inhibitor of Mannoside acetyl glucosaminyltransferase 5 (MGAT5), used for studying glioblastoma multiforme (GBM). PST3.1a inhibits TGF-βR and FAK signalling associated with doublecortin (DCX), increases OLIG2 expression, and suppresses the invasion and proliferation of GBM initiator cells (GICs).

Formula: C₃₂H₃₃O₆P

Color and Shape: Solid

Molecular weight: 544.57

Ref: TM-T202996