CAS 109713-79-3: Neldazosin

Description: Neldazosin is a pharmaceutical compound primarily classified as an alpha-1 adrenergic antagonist, which is used in the treatment of hypertension and benign prostatic hyperplasia (BPH). Its mechanism of action involves blocking alpha-1 adrenergic receptors, leading to vasodilation and a subsequent decrease in blood pressure. Neldazosin is characterized by its ability to selectively inhibit these receptors, which helps alleviate urinary symptoms associated with BPH by relaxing smooth muscle in the prostate and bladder neck. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other medications in its class. In terms of chemical properties, Neldazosin has a specific molecular structure that contributes to its pharmacological activity, and it is often studied for its potential interactions with other medications. As with any pharmaceutical agent, it is essential to consider its pharmacokinetics, including absorption, distribution, metabolism, and excretion, to understand its efficacy and safety in clinical use.

Formula: C₁₈H₂₅N₅O₄

InChI: InChI=1S/C18H25N5O4/c1-11(24)8-16(25)22-4-6-23(7-5-22)18-20-13-10-15(27-3)14(26-2)9-12(13)17(19)21-18/h9-11,24H,4-8H2,1-3H3,(H2,19,20,21)

InChI key: InChIKey=IOSMPEJNAQZKJT-UHFFFAOYSA-N

SMILES: O=C(N1CCN(C=2N=C(N)C=3C=C(OC)C(OC)=CC3N2)CC1)CC(O)C

Synonyms:

• 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(3-hydroxy-1-oxobutyl)piperazine
• 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(3-hydroxybutyryl)piperazine
• 1-Butanone, 1-[4-(4-amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-3-hydroxy-
• 1-[4-(4-Amino-6,7-Dimethoxyquinazolin-2-Yl)Piperazin-1-Yl]-3-Hydroxybutan-1-One
• 1-[4-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-1-piperazinyl]-3-hydroxy-1-butanone
• Hro 2/145
• Neldazosin [INN]
• Neldazosina
• Neldazosina [INN-Spanish]
• Neldazosine
• Neldazosine [INN-French]
• Neldazosinum
• Neldazosinum [INN-Latin]
• Piperazine, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(3-hydroxy-1-oxobutyl)-
• Unii-G3E7Ro42Mb
• Neldazosin

Neldazosin

CAS: 109713-79-3

Neldazosin is used as a potent α1-adrenoceptor antagonist.

• Formula: C₁₈H₂₅N₅O₄
• Purity: 100% - 99.87%
• Color and Shape: Liquid
• Molecular weight: 375.42