CAS 1098-45-9

Pregnanetriol

Description:

Pregnanetriol, with the CAS number 1098-45-9, is a steroidal compound that is a metabolite of progesterone. It is characterized by its three hydroxyl (-OH) groups, which contribute to its classification as a triol. This compound is typically found in biological systems, particularly in the context of steroid metabolism, and plays a role in various physiological processes. Pregnanetriol is often studied for its potential implications in reproductive health and hormonal regulation. Its structure allows it to interact with steroid hormone receptors, influencing biological pathways. Additionally, it is important in the context of certain clinical assessments, such as monitoring pregnancy and evaluating adrenal function. Pregnanetriol is generally soluble in organic solvents and exhibits moderate stability under standard laboratory conditions. As with many steroid derivatives, its biological activity and effects can be influenced by its concentration and the presence of other hormones or metabolites in the system.

Formula: C₂₁H₃₆O₃

InChI: InChI=1S/C21H36O3/c1-13(22)21(24)11-8-18-16-5-4-14-12-15(23)6-9-19(14,2)17(16)7-10-20(18,21)3/h13-18,22-24H,4-12H2,1-3H3/t13-,14+,15+,16+,17-,18-,19-,20-,21-/m0/s1

InChI key: InChIKey=SCPADBBISMMJAW-UHHUKTEYSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(CC1)[H])[H])(CC[C@@]2([C@H](C)O)O)[H]

Synonyms:

• 5β-Pregnane-3α,17α,20α-triol
• Pregnane-3,17,20-triol, (3α,5β,20S)-
• 3α,17α,20α-Trihydroxy-5β-pregnane
• (3α,5β,20S)-Pregnane-3,17,20-triol
• 5β-Pregnane-3α,17,20α-triol

Pregnanetriol

CAS: 1098-45-9

Formula: C₂₁H₃₆O₃

Molecular weight: 336.52

Ref: 4Z-P-467001

Pregnanetriol

CAS: 1098-45-9

Pregnanetriol, a metabolite from 17α-hydroxyprogesterone, indicates 21-hydroxylase deficiency when urinary levels are high.

Formula: C₂₁H₃₆O₃

Color and Shape: Solid

Molecular weight: 336.516

Ref: TM-T35665

Pregnanetriol

CAS: 1098-45-9

Applications Pregnanetriol is a steroid present at elevated levels in the urine of patients with congenital adrenal hyperplasma. During treatment with cortisol replacement, elevated urine Pregnanetriol levels indicate insufficient dosage of cortisol. Pregnanetriol is also one of the urinary marker for adrenal incidentaloma. Pregnanetriol is a metabolite of Androstenedione (A637550).
References Kinoshita, K. et al.: J. Clin. Endocrinol., 26, 1219 (1966); Kotlowska, A. et al.: Clin. Biochem., 42, 448 (2009); Wang, J. et al.: Zhipu Xue., 25, 201 (2004);

Formula: C₂₁H₃₆O₃

Color and Shape: White

Molecular weight: 336.51

Ref: TR-P705160

Pregnanetriol-d4

Controlled Product

CAS: 1098-45-9

Applications Labelled Pregnanetriol, a steroid present at elevated levels in the urine of patients with congenital adrenal hyperplasma. During treatment with cortisol replacement, elevated urine Pregnanetriol levels indicate insufficient dosage of cortisol. Pregnanetriol is also one of the urinary marker for adrenal incidentaloma. Pregnanetriol is a metabolite of Androstenedione (A637550).
References Kinoshita, K. et al.: J. Clin. Endocrinol., 26, 1219 (1966); Kotlowska, A. et al.: Clin. Biochem., 42, 448 (2009); Wang, J. et al.: Zhipu Xue., 25, 201 (2004);

Formula: C₂₁D₄H₃₂O₃

Color and Shape: Neat

Molecular weight: 340.53

Ref: TR-P705162

Pregnantriol

Controlled Product

CAS: 1098-45-9

Pregnantriol is a naturally occurring steroid hormone that is produced in the placenta and the adrenal glands. Pregnantriol has been shown to be a potent inducer of liver cells, which may be due to its ability to bind to enzymes that are involved in lipid metabolism. This compound has also been shown to have diagnostic properties and is used as a diagnostic agent for adrenocortical carcinoma, urinary tract infections, metabolic disorders, and acid formation. Pregnantriol can be detected using fluorescence detection.

Formula: C₂₁H₃₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 336.51 g/mol

Ref: 3D-FP65139