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CAS 109881-25-6

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2,6-diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside

Description:
2,6-Diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside, with the CAS number 109881-25-6, is a nucleoside analog derived from purine. It features a purine base, specifically 2,6-diaminopurine, linked to a modified ribose sugar that lacks the hydroxyl groups at the 2' and 3' positions, making it a dideoxyribonucleoside. This structural modification imparts unique biochemical properties, particularly in its ability to inhibit viral replication and its potential use in antiviral therapies. The compound exhibits a higher affinity for viral polymerases compared to host polymerases, which can enhance its effectiveness as an antiviral agent. Additionally, its structural characteristics allow it to mimic natural nucleosides, facilitating incorporation into nucleic acids during replication. The compound is of interest in medicinal chemistry and virology, particularly in the development of treatments for viral infections and certain cancers. However, its pharmacokinetics, toxicity, and efficacy in clinical settings require thorough investigation to establish its therapeutic potential.
Formula:C10H12N6O2
InChI:InChI=1/C10H12N6O2/c11-8-7-9(15-10(12)14-8)16(4-13-7)6-2-1-5(3-17)18-6/h1-2,4-6,17H,3H2,(H4,11,12,14,15)/t5-,6+/m0/s1
Synonyms:
  • Ddedapr
  • D4DAP
  • [(2S,5R)-5-(2,6-diamino-9H-purin-9-yl)-2,5-dihydrofuran-2-yl]methanol
  • 2,6-Diaminopurine 2',3'-didehydro-2',3'-dideoxyriboside
  • Adenosine, 2-amino-2',3'-didehydro-2',3'-dideoxy-
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