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CAS 1100-22-7

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Dansyl-L-leucine

Description:
Dansyl-L-leucine is a chemical compound characterized by its fluorescent properties, primarily due to the dansyl group, which is a sulfonamide derivative of 2-amino-5-dimethylaminonaphthalene-1-sulfonic acid. This compound is often utilized in biochemistry and molecular biology for labeling and tracking peptides and proteins, as the dansyl moiety emits fluorescence upon excitation, allowing for sensitive detection. Dansyl-L-leucine is an amino acid derivative, featuring the L-leucine structure, which contributes to its role in peptide synthesis and protein studies. It is soluble in polar solvents, making it suitable for various biochemical applications. The compound is also known for its ability to form stable conjugates with amines, which is advantageous in the study of protein interactions and dynamics. Additionally, dansyl derivatives are often employed in chromatography and spectroscopic techniques due to their distinct spectral properties. Overall, Dansyl-L-leucine serves as a valuable tool in research involving protein labeling and analysis.
Formula:C18H24N2O4S
InChI:InChI=1S/C18H24N2O4S/c1-12(2)11-15(18(21)22)19-25(23,24)17-10-6-7-13-14(17)8-5-9-16(13)20(3)4/h5-10,12,15,19H,11H2,1-4H3,(H,21,22)/t15-/m0/s1
InChI key:InChIKey=XBMQRPDOXIPUFG-HNNXBMFYSA-N
SMILES:S(N[C@@H](CC(C)C)C(O)=O)(=O)(=O)C=1C2=C(C(N(C)C)=CC=C2)C=CC1
Synonyms:
  • 1-Dimethylaminonaphthalene-5-sulfonyl-<span class="text-smallcaps">L</span>-leucine
  • <span class="text-smallcaps">L</span>-Dansylleucine
  • <span class="text-smallcaps">L</span>-Leucine, N-[[5-(dimethylamino)-1-naphthalenyl]sulfonyl]-
  • DNS-leucine
  • Dansyl-<span class="text-smallcaps">L</span>-leucine
  • Dansyl-l-leucine
  • Dansylleucine
  • Leucine, N-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-
  • Leucine, N-[[5-(dimethylamino)-1-naphthyl]sulfonyl]-, <span class="text-smallcaps">L</span>-
  • N-Dansyl-<span class="text-smallcaps">L</span>-leucine
  • See more synonyms
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