CAS 110011-82-0

(+)-Nefopam

Description:

(+)-Nefopam is a synthetic analgesic compound primarily used for the management of pain. It belongs to the class of non-opioid analgesics and is known for its unique mechanism of action, which involves the inhibition of the reuptake of neurotransmitters such as serotonin, norepinephrine, and dopamine. This action contributes to its analgesic effects without the typical side effects associated with opioids. The substance is characterized by its chiral nature, with the (+) designation indicating its specific enantiomeric form, which is biologically active. Nefopam is typically administered orally and has a relatively rapid onset of action. It is important to note that while it is effective for pain relief, it may also cause side effects such as dizziness, nausea, and potential cardiovascular effects. Due to its non-opioid nature, it is sometimes considered a safer alternative for patients at risk of opioid dependence. Overall, (+)-Nefopam represents a valuable option in pain management, particularly in settings where opioid use is to be minimized.

Formula: C₁₇H₁₉NO

InChI: InChI=1S/C17H19NO/c1-18-11-12-19-17(14-7-3-2-4-8-14)16-10-6-5-9-15(16)13-18/h2-10,17H,11-13H2,1H3/t17-/m0/s1

InChI key: InChIKey=RGPDEAGGEXEMMM-KRWDZBQOSA-N

SMILES: CN1CC=2C([C@@H](OCC1)C3=CC=CC=C3)=CC=CC2

Synonyms:

• 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, (S)-
• 1H-2,5-Benzoxazocine, 3,4,5,6-tetrahydro-5-methyl-1-phenyl-, (1S)-
• (1S)-3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine
• S-Nefopam
• (+)-Nefopam

(S)-(+)-Nefopam

CAS: 110011-82-0

Formula: C₁₇H₁₉NO

Molecular weight: 253.35

Ref: 4Z-N-3714

(+)-Nefopam

CAS: 110011-82-0

(+)-Nefopam is a medicinal analog that acts as an inhibitor of various kinases, including Chinese hamster ovary cell kinase and tumor-associated kinases. It has been shown to have anticancer effects by inhibiting the growth of cancer cells and inducing apoptosis. (+)-Nefopam is excreted primarily in urine and has been found to bind to proteins in human plasma. This potent inhibitor has promising potential for use as an anticancer drug in the future.

Formula: C₁₇H₁₉NO

Purity: Min. 95%

Molecular weight: 253.34 g/mol

Ref: 3D-KEA01182