CAS 11006-55-6

sodium N-(N-choloylglycyl)taurinate

Description:

Sodium N-(N-choloylglycyl)taurinate, also known as sodium choloylglycinate, is a bile acid derivative that exhibits surfactant properties. It is a sodium salt formed from the conjugation of taurine and choloylglycine, which is a component of bile acids. This compound is characterized by its amphiphilic nature, possessing both hydrophilic and hydrophobic regions, which allows it to interact with lipids and proteins effectively. It is often utilized in biochemical and pharmaceutical applications, particularly in drug formulation and delivery systems, due to its ability to enhance solubility and bioavailability of hydrophobic compounds. Additionally, sodium N-(N-choloylglycyl)taurinate may play a role in digestive processes, mimicking the action of natural bile salts. Its safety profile and biocompatibility make it a candidate for various therapeutic applications, although specific toxicity and pharmacokinetic data should be reviewed for clinical use. Overall, this compound is significant in both research and practical applications within the fields of biochemistry and pharmacology.

Formula: C₂₈H₄₇N₂NaO₈S

InChI: InChI=1/C28H48N2O8S.Na/c1-16(4-7-24(34)30-15-25(35)29-10-11-39(36,37)38)19-5-6-20-26-21(14-23(33)28(19,20)3)27(2)9-8-18(31)12-17(27)13-22(26)32;/h16-23,26,31-33H,4-15H2,1-3H3,(H,29,35)(H,30,34)(H,36,37,38);/q;+1/p-1/t16-,17+,18-,19-,20?,21?,22-,23+,26?,27+,28-;/m1./s1

SMILES: CC(CCC(=NCC(=NCCS(=O)(=O)O)O)O)C1CCC2C3C(CC(C12C)O)C1(C)CCC(CC1CC3O)O.[Na]

Synonyms:

• 2-[[[[(3A,5B,7A,12A)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]Acetyl]Amino]-Ethanesulfonic Acid Monosodium Salt
• Ethanesulfonic Acid, 2-[[[[(3Alpha,5Beta,7Alpha,12Alpha)-3,7,12-Trihydroxy-24-Oxocholan-24-Yl]Amino]Acetyl]Amino]-, Monosodium Salt
• Sodium Glycotaurocholate
• Sodium Tauroglycocholate
• Tauroglycocholic acid, sodium salt
• sodium 2-({N-[(3alpha,5beta,7alpha,8xi,9xi,12alpha,14xi)-3,7,12-trihydroxy-24-oxocholan-24-yl]glycyl}amino)ethanesulfonate
• sodium N-(N-choloylglycyl)taurinateTauroglycocholic acid sodium salt