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CAS 110084-95-2

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des-his1,(glu9)-glucagon amide

Description:
Des-His1,(Glu9)-glucagon amide is a synthetic peptide that is a modified form of glucagon, a hormone produced by the pancreas that plays a crucial role in glucose metabolism. This particular variant has specific amino acid substitutions that enhance its biological activity and stability compared to native glucagon. The modification at the first position (removal of histidine) and the substitution of glutamic acid at the ninth position contribute to its unique pharmacological properties. Des-His1,(Glu9)-glucagon amide is known for its ability to stimulate glycogenolysis and gluconeogenesis, thereby increasing blood glucose levels. It is often studied for its potential therapeutic applications in conditions such as diabetes and obesity. The amide form indicates that the peptide has been modified to enhance its stability and bioavailability. Overall, this compound is of significant interest in both research and clinical settings due to its role in metabolic regulation and potential as a therapeutic agent.
Formula:C148H221N41O47S
Synonyms:
  • (Des-His1,Glu9)-Glucagon (1-29) amide (human, bovine, porcine)
  • H-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Glu-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-Val-Gln-Trp-Leu-Met-Asn-Thr-NH2
  • M.W. 3358.65 C148H221N41O47S
  • DES-HIS1,[GLU9]-GLUCAGON AMIDE
  • 1-De-His-glucagon amide
  • des-his(1)-glucagonamid
  • glucagon amide, des-His(1)-
  • Glucagon amide, des-histidine(1)-
  • DES-HIS1-[GLU9]-GLUCAGON (1-29) AMIDE
  • Glucagon (pig), 1-de-L-histidine-9-L-glutamic acid-29-L-threoninamide-
  • See more synonyms
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