CAS 110101-66-1

Tirilazad

Description:

Tirilazad, with the CAS number 110101-66-1, is a synthetic compound classified as a neuroprotective agent. It belongs to the class of compounds known as 21-aminosteroids and is primarily recognized for its ability to inhibit lipid peroxidation, thereby protecting cell membranes from oxidative damage. Tirilazad has been studied for its potential therapeutic effects in conditions associated with oxidative stress, such as stroke and traumatic brain injury. The compound exhibits a unique mechanism of action by modulating the activity of free radicals and reducing inflammation. It is typically administered in a clinical setting and has been evaluated for its efficacy in various neurological disorders. Tirilazad is characterized by its relatively low solubility in water, which can influence its bioavailability and pharmacokinetics. Safety and toxicity profiles have been assessed in clinical trials, contributing to its understanding as a potential treatment option. Overall, Tirilazad represents a significant area of research in neuroprotection and oxidative stress management.

Formula: C₃₈H₅₂N₆O₂

InChI: InChI=1S/C38H52N6O2/c1-26-22-31-29-9-8-27-23-28(45)10-12-37(27,2)30(29)11-13-38(31,3)35(26)32(46)25-41-18-20-43(21-19-41)34-24-33(42-14-4-5-15-42)39-36(40-34)44-16-6-7-17-44/h10-12,23-24,26,29,31,35H,4-9,13-22,25H2,1-3H3/t26-,29-,31+,35-,37+,38+/m1/s1

InChI key: InChIKey=RBKASMJPSJDQKY-RBFSKHHSSA-N

SMILES: C[C@@]12[C@]([C@]3(C([C@]4(C)C(CC3)=CC(=O)C=C4)=CC1)[H])(C[C@@H](C)[C@@H]2C(CN5CCN(CC5)C=6C=C(N=C(N6)N7CCCC7)N8CCCC8)=O)[H]

Synonyms:

• (16α)-21-[4-(2,6-Di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16-methylpregna-1,4,9(11)-triene-3,20-dione
• Tirilazad
• Pregna-1,4,9(11)-triene-3,20-dione, 21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16-methyl-, (16α)-
• U 74006
• PNU 74006F

Tirilazad

CAS: 110101-66-1

Tirilazad: a 21-aminosteroid preventing lipid peroxidation; aids in neuroprotection and treats ischemic conditions.

Formula: C₃₈H₅₂N₆O₂

Color and Shape: Solid

Molecular weight: 624.86

Ref: TM-T73989