CAS 110101-67-2

Tirilazad mesylate

Description:

Tirilazad mesylate is a synthetic compound that belongs to the class of neuroprotective agents, primarily known for its role as a free radical scavenger. It is characterized by its ability to inhibit lipid peroxidation, thereby protecting neuronal cells from oxidative stress and damage. This compound is often studied for its potential therapeutic applications in conditions such as stroke, traumatic brain injury, and spinal cord injury. Tirilazad mesylate is typically administered in its mesylate salt form, which enhances its solubility and bioavailability. The substance is known for its relatively low toxicity profile, making it a candidate for clinical use. Its mechanism of action involves the modulation of various signaling pathways associated with cell survival and apoptosis. Additionally, Tirilazad mesylate has been investigated for its effects on inflammation and neurodegeneration, contributing to ongoing research in neuropharmacology. Overall, its unique properties make it a significant subject of study in the field of neuroprotective therapies.

Formula: C₃₈H₅₂N₆O₂·CH₄O₃S

InChI: InChI=1S/C38H52N6O2.CH4O3S/c1-26-22-31-29-9-8-27-23-28(45)10-12-37(27,2)30(29)11-13-38(31,3)35(26)32(46)25-41-18-20-43(21-19-41)34-24-33(42-14-4-5-15-42)39-36(40-34)44-16-6-7-17-44;1-5(2,3)4/h10-12,23-24,26,29,31,35H,4-9,13-22,25H2,1-3H3;1H3,(H,2,3,4)/t26-,29-,31+,35-,37+,38+;/m1./s1

InChI key: InChIKey=HPZOOQSXPMEJBV-ODCFVKFUSA-N

SMILES: C[C@@]12[C@]([C@]3(C([C@]4(C)C(CC3)=CC(=O)C=C4)=CC1)[H])(C[C@@H](C)[C@@H]2C(CN5CCN(CC5)C=6C=C(N=C(N6)N7CCCC7)N8CCCC8)=O)[H].S(C)(=O)(=O)O

Synonyms:

• (16Alpha)-21-{4-[2,6-Di(Pyrrolidin-1-Yl)Pyrimidin-4-Yl]Piperazin-1-Yl}-16-Methylpregna-1,4,9(11)-Triene-3,20-Dione Methanesulfonate (1:1)
• 21-(4-(2,6-di-1-Pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methylpregna-1,4,9(11)-triene-3,20-dione monomethanesulfonate
• Freedox
• Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, monomethanesulfonate
• Pregna-1,4,9(11)-triene-3,20-dione, 21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16-methyl-, (16α), methanesulfonate (1:1)
• Pregna-1,4,9(11)-triene-3,20-dione, 21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16-methyl-, (16α)-, monomethanesulfonate
• Tirilazad mesylate
• U 74006F
• U74006F
• Unii-19B418Dv39

Tirilazad mesylate

CAS: 110101-67-2

Tirilazad mesylate

Purity: ≥98%

Molecular weight: 720.96g/mol

Ref: 54-BUP08294

Tirilazad mesylate

CAS: 110101-67-2

Tirilazad mesylate (U 74006F) is a lipid peroxidation inhibitor with antiviral activity.Tirilazad mesylate is used in the study of neurological disorders.

Formula: C₃₉H₅₆N₆O₅S

Purity: 99.65% - 99.75%

Color and Shape: Solid

Molecular weight: 720.96

Ref: TM-T28978