CAS 110115-07-6

N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide

Description:

N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide, with CAS number 110115-07-6, is a synthetic compound that belongs to the class of peptides and derivatives. It features a complex structure characterized by the presence of two leucine amino acids, an acetyl group, and a formyl group attached to a propyl chain that includes a methylthio substituent. This compound is typically studied for its potential biological activities, including its role in peptide synthesis and its interactions with biological systems. The presence of the acetyl and formyl groups suggests that it may exhibit specific reactivity and stability under certain conditions. Additionally, the methylthio group can influence the compound's lipophilicity and overall solubility in various solvents. As a peptide derivative, it may also be of interest in medicinal chemistry and drug design, particularly in the development of therapeutics targeting specific biological pathways. However, detailed studies on its pharmacological properties and mechanisms of action would be necessary to fully understand its potential applications.

Formula: C₁₉H₃₅N₃O₄S

InChI: InChI=1S/C19H35N3O4S/c1-12(2)9-16(20-14(5)24)19(26)22-17(10-13(3)4)18(25)21-15(11-23)7-8-27-6/h11-13,15-17H,7-10H2,1-6H3,(H,20,24)(H,21,25)(H,22,26)/t15-,16-,17-/m0/s1

InChI key: InChIKey=RJWLAIMXRBDUMH-ULQDDVLXSA-N

SMILES: [C@@H](NC([C@H](CC(C)C)NC(C)=O)=O)(C(N[C@@H](CCSC)C=O)=O)CC(C)C

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-
• <span class="text-smallcaps">L</smallcap>-Leucinamide, N-acetyl-<smallcap>L</span>-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-
• Ac-Leu-Leu-Met-aldehyde
• Ac-Leu-Leu-methioninal
• Allm
• Calp II
• Calpain Inhibitor II
• N-Acetyl-<span class="text-smallcaps">L</smallcap>-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-<smallcap>L</span>-leucinamide
• N-Acetyl-L-leucyl-L-leucyl-L-methioninal
• N-acetyl-L-leucyl-N-[(1R)-1-formyl-3-(methylsulfanyl)propyl]-L-leucinamide
• N-acetyl-L-leucyl-N-[(2S)-4-(methylsulfanyl)-1-oxobutan-2-yl]-L-leucinamide
• N-acetylleucyl-N-[4-(methylsulfanyl)-1-oxobutan-2-yl]leucinamide
• Suam 312
• L-Leucinamide, N-acetyl-L-leucyl-N-[1-formyl-3-(methylthio)propyl]-, (S)-
• N-Acetyl-L-leucyl-N-[(1S)-1-formyl-3-(methylthio)propyl]-L-leucinamide

Calpain inhibitor II

CAS: 110115-07-6

Calpain inhibitor II

Formula: C₁₉H₃₅N₃O₄S

Purity: By hplc: >95% (Typical Value in Batch COA)

Color and Shape: white to off-white powder

Molecular weight: 401.56g/mol

Ref: 54-BIC8320

Calpain Inhibitor II

CAS: 110115-07-6

Inhibitor of calpain, a calcium-dependent cysteine protease which is implicated in the apoptosis as well as in synaptic plasticity, where it was seen to block long-term potentiation. Calpain inhibitor II has also antiviral properties as it was shown to inhibit the main protease Mpro (3CLpro) from SARS-CoV-2 with IC50 of 0.97 μM.

Formula: C₁₉H₃₅N₃O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 401.57 g/mol

Ref: 3D-FC29615

Ac-Leu-Leu-Met-H (Aldehyde)

CAS: 110115-07-6

Ac-Leu-Leu-Met-H (Aldehyde) is a tetrazolium dye that is used as a biological stain for the detection of bacteria in infectious diseases. It binds to toll-like receptor 4 on macrophages and other cells, which triggers a cascade of events leading to bacterial cell lysis. Aldehyde also has been shown to be an autophagy inducer and can cause neuronal death when administered in high doses.

Formula: C₁₉H₃₅N₃O₄S

Purity: Min. 95%

Molecular weight: 401.57 g/mol

Ref: 3D-IAL-3678-PI

ALLM

CAS: 110115-07-6

ALLM (Calpain inhibitor II), a potent calpain and cathepsin protease inhibitor, not only prevents neuronal cell death but also enhances chronic neurological function following spinal cord injury (SCI)[1][2].

Formula: C₁₉H₃₅N₃O₄S

Purity: 98%

Color and Shape: White Powder

Molecular weight: 401.56

Ref: TM-T14187