Lanatoside is a cardiac glycoside derived from the leaves of the plant Digitalis lanata, commonly known as woolly foxglove. It is primarily used in the treatment of heart conditions, particularly heart failure and certain types of arrhythmias, due to its ability to increase the force of myocardial contraction and regulate heart rhythm. The chemical structure of lanatoside includes a steroid nucleus with a sugar moiety, which contributes to its pharmacological activity. It exhibits a relatively high affinity for the Na+/K+ ATPase enzyme, leading to increased intracellular calcium levels in cardiac cells. Lanatoside is characterized by its potent effects, but it also has a narrow therapeutic window, necessitating careful monitoring of dosage to avoid toxicity. Common side effects may include gastrointestinal disturbances, visual changes, and arrhythmias. As with other cardiac glycosides, its use requires consideration of patient-specific factors, including renal function and potential drug interactions. Overall, lanatoside is an important compound in cardiology, reflecting the complex interplay between plant-derived substances and modern medicine.

Lanatoside is an FDA approved cardiac glycoside was identified as a candidate anti-dengue compound.

Lanatoside

11014-59-8: Lanatoside is a cardiac glycoside derived from the leaves of the plant Digitalis lanata, commonly known as woolly foxglove. It is primarily used in the treatment of heart conditions, particularly heart failure and certain types of arrhythmias, due to its ability to increase the force of myocardial contraction and regulate heart rhythm. The chemical structure of lanatoside includes a steroid nucleus with a sugar moiety, which contributes to its pharmacological activity. It exhibits a relatively high affinity for the Na+/K+ ATPase enzyme, leading to increased intracellular calcium levels in cardiac cells. Lanatoside is characterized by its potent effects, but it also has a narrow therapeutic window, necessitating careful monitoring of dosage to avoid toxicity. Common side effects may include gastrointestinal disturbances, visual changes, and arrhythmias. As with other cardiac glycosides, its use requires consideration of patient-specific factors, including renal function and potential drug interactions. Overall, lanatoside is an important compound in cardiology, reflecting the complex interplay between plant-derived substances and modern medicine.

<p>Lanatoside: FDA-approved cardiac glycoside, anti-dengue, promotes atherosclerosis, anti-tumor for colorectal and liver cancer.</p>

CAS 11014-59-8

Lanatoside

Lanatoside

Ref: TM-T25611