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CAS 110143-10-7

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Lodenosine

Description:
Lodenosine, with the CAS number 110143-10-7, is a purine nucleoside analog that has garnered interest in the field of medicinal chemistry, particularly for its potential therapeutic applications. It is characterized by its structural similarity to adenosine, which allows it to interact with adenosine receptors in biological systems. This interaction can influence various physiological processes, including immune response and cellular signaling. Lodenosine has been studied for its potential use in treating conditions such as cancer and viral infections, as it may exhibit antiviral and antitumor properties. The compound's pharmacological profile includes its ability to modulate nucleoside transport and metabolism, which can enhance its efficacy in certain therapeutic contexts. Additionally, its solubility and stability under physiological conditions are important factors that influence its bioavailability and overall effectiveness as a drug candidate. Ongoing research continues to explore its mechanisms of action and potential applications in clinical settings.
Formula:C10H12FN5O2
InChI:InChI=1S/C10H12FN5O2/c11-6-1-5(2-17)18-10(6)16-4-15-7-8(12)13-3-14-9(7)16/h3-6,10,17H,1-2H2,(H2,12,13,14)/t5-,6-,10+/m0/s1
InChI key:InChIKey=KBEMFSMODRNJHE-JFWOZONXSA-N
SMILES:F[C@@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)C1
Synonyms:
  • 2′-β-Fluoro-2′,3′-dideoxyadenosine
  • 9-(2,3-Dideoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-threo-pentofuranosyl)-9H-purin-6-amine
  • 9-(2,3-Dideoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-threo-pentofuranosyl)adenine
  • 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)-9H-purin-6-amine
  • 9-(2,3-dideoxy-2-fluoropentofuranosyl)-9H-purin-6-amine
  • 9H-Purin-6-amine, 9-(2,3-dideoxy-2-fluoro-β-<span class="text-smallcaps">D</span>-threo-pentofuranosyl)-
  • F-ddA
  • Lodenosine
  • Lodensine
  • NSC 613792
  • See more synonyms
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Found 4 products.
  • 6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine
    Biosynth
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    6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine

    CAS:
    <p>6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine is a nucleoside analog that is used to treat HIV. It is a prodrug that undergoes phosphorylation by host cell kinases to form its active form, 2'-deoxycytidine monophosphate (2'DCPM). This drug has been shown to inhibit the replication of HIV in vitro and in vivo. 6-Amino-9-(2',3'-dideoxy-2'-fluoro-β-D-arabinofuranosyl)purine has antiviral potency against both group M and N HIV isolates. It also enhances polymerase chain reaction amplification of HIV DNA and can be used in tissue culture experiments to study the effects of drugs on the virus. Clinical trials have shown that 6-amino 9-(2',3'-dideoxy-2</p>
    Formula:C10H12FN5O2
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:253.24 g/mol

    Ref: 3D-NA05179

    ne
    To inquire
  • 6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine
    TRC
    + Info

    6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine

    Controlled Product
    CAS:
    Formula:C10H12FN5O2
    Color and Shape:Neat
    Molecular weight:253.233

    Ref: TR-A212325

    100mg
    2,087.00€
  • 6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine-13C5
    TRC
    + Info

    6-Amino-9-(2',3'-dideoxy-2'-fluoro-b-D-arabinofuranosyl)purine-13C5

    Controlled Product
    CAS:
    Formula:C5C5H12FN5O2
    Color and Shape:Neat
    Molecular weight:258.196

    Ref: TR-A212327

    25mg
    19,421.00€
  • Lodenosine
    Targetmol
    + Info

    Lodenosine

    CAS:
    Lodenosine is an inhibitor of RNA-directed DNA polymerase, and potentially for the treatment of HIV.
    Formula:C10H12FN5O2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:253.23

    Ref: TM-T19688