CAS 11018-89-6: Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, hydrate (1:8), (1β,3β,5β,11α)-

Description: Card-20(22)-enolide, specifically identified by its CAS number 11018-89-6, is a complex organic compound belonging to the class of cardenolides, which are steroidal glycosides. This substance features a steroid backbone with multiple hydroxyl groups, contributing to its hydrophilic properties. The presence of a sugar moiety, specifically a 6-deoxy-α-L-mannopyranosyl group, enhances its solubility in water and influences its biological activity. The compound is characterized by its specific stereochemistry, denoted by the (1β,3β,5β,11α) configuration, which is crucial for its interaction with biological targets, particularly in the context of cardiac glycosides. Card-20(22)-enolide is typically found in a hydrated form, indicating the presence of water molecules in its crystalline structure, which can affect its stability and solubility. This compound is of interest in pharmacology due to its potential therapeutic effects, particularly in the treatment of heart conditions, as it may influence cardiac contractility and rhythm.

Formula: C₂₉H₄₄O₁₂·8H₂O

InChI: InChI=1S/C29H44O12.8H2O/c1-13-22(34)23(35)24(36)25(40-13)41-15-8-19(32)28(12-30)21-17(3-5-27(28,37)9-15)29(38)6-4-16(14-7-20(33)39-11-14)26(29,2)10-18(21)31;;;;;;;;/h7,13,15-19,21-25,30-32,34-38H,3-6,8-12H2,1-2H3;8*1H2/t13-,15-,16+,17+,18+,19+,21+,22-,23+,24+,25-,26+,27-,28+,29-;;;;;;;;/m0......../s1

InChI key: InChIKey=TYBARJRCFHUHSN-DMJRSANLSA-N

SMILES: O=C1OCC(=C1)C2CCC3(O)C4CCC5(O)CC(OC6OC(C)C(O)C(O)C6O)CC(O)C5(CO)C4C(O)CC23C.O

Synonyms:

• (1beta,3beta,5beta,11alpha)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide
• (1beta,3beta,5beta,8xi,9xi,11alpha)-3-[(6-deoxy-alpha-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide
• Card-20(22)-enolide, 3-[(6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, hydrate (1:8), (1β,3β,5β,11α)-
• Card-20(22)-enolide, 3-[(6-deoxy-α-<span class="text-smallcaps">L</span>-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, octahydrate, (1β,3β,5β,11α)-
• G-Strophantin octahydrate
• Strophantine octahydrate
• Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, octahydrate, (1β,3β,5β,11α)-
• Ouabain octahydrate
• Card-20(22)-enolide, 3-[(6-deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxy-, hydrate (1:8), (1β,3β,5β,11α)-

Ouabain octahydrate, 95%

CAS: 11018-89-6

Ouabain, as well as other endogenous digitalis-like compounds, can down-regulate the expression of 14-3-3 proteins …

• Formula: C₂₉H₆₀O₂₀
• Purity: 95%
• Color and Shape: White to off-white to pale yellow, Powder
• Molecular weight: 728.78

Ouabain CRS

CAS: 11018-89-6

• Formula: C₂₉H₄₄O₁₂
• Color and Shape: Powder
• Molecular weight: 584.6525

Ouabain octahydrate

CAS: 11018-89-6

Ouabain octahydrate (Acocantherine) is a cardiac glycoside that inhibits Na(+)/K(+) ATPase. Ouabain octahydrate regulates transcription …

• Formula: C₂₉H₄₄O₁₂·8H₂O
• Purity: 98% - 99.36%
• Color and Shape: Solid
• Molecular weight: 728.77

Ouabain octahydrate, 95%

CAS: 11018-89-6

• Formula: C₂₉H₄₄O₁₂· 8H₂O
• Purity: ≥ 95.0%
• Color and Shape: White or off-white powder
• Molecular weight: 728.78

Ouabain octahydrate, EP grade

CAS: 11018-89-6

• Formula: C₂₉H₄₄O₁₂· 8H₂O
• Purity: ≥ 96.0%
• Color and Shape: A white or almost white, crystalline powder or colourless crystals
• Molecular weight: 728.78

Ouabain octahydrate, 96%

CAS: 11018-89-6

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₉H₆₀O₂₀
• Purity: 96%
• Color and Shape: White to off-white, Crystalline powder
• Molecular weight: 728.78

Ouabain Octahydrate

CAS: 11018-89-6

• Formula: C₂₉H₄₄O₁₂H₂O
• Color and Shape: Neat
• Molecular weight: 728.77

Ouabain Octahydrate

CAS: 11018-89-6

Applications A cardiac glycoside that inhibits Na(+)/K(+) ATPase. It regulates transcription of MDR (increase, Pgp) …

• Formula: C₂₉H₄₄O₁₂H₂O
• Color and Shape: White To Off-White
• Molecular weight: 728.77

Ouabain octahydrate

CAS: 11018-89-6

Na+/K+-ATPase inhibitor

• Formula: C₂₉H₄₄O₁₂·8H₂O
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 728.77 g/mol