CAS 1101810-02-9

N-[4-[4-[1-(cyclopropylsulfonyl)cyclopropyl]-6-[(3S)-3-methyl-4-morpholinyl]-2-pyrimidinyl]phenyl]-N'-(2-hydroxyethyl)-thiourea

CAS: 1101810-02-9

Formula: C₂₄H₃₁N₅O₄S₂

Purity: 98%

Molecular weight: 517.6640

Ref: IN-DA01EPQM

AZD 3147

CAS: 1101810-02-9

AZD 3147

Purity: ≥98%

Molecular weight: 517.66g/mol

Ref: 54-BUP02471

AZD3147

CAS: 1101810-02-9

AZD3147 is a small molecule that inhibits leukemia inhibitory factor (LIF) and consequently prevents the proliferation of pluripotent stem cells. It can be used to treat cancer and other diseases where LIF is an important factor. AZD3147 has been shown to have a high affinity for the LIF receptor and low affinity for other receptors, which helps to reduce its potential side effects. In addition, this drug has physicochemical properties that allow it to cross the blood-brain barrier. The pharmacokinetics of AZD3147 in animals have been studied at nanomolar concentrations, showing promising results.

Formula: C₂₄H₃₁N₅O₄S₂

Purity: Min. 95%

Molecular weight: 517.7 g/mol

Ref: 3D-BUB81002

AZD 3147

CAS: 1101810-02-9

AZD 3147 inhibits mTORC1 (40.7 nM), mTORC2 (5.75 nM), and PI3Kα/β/δ/γ (912/5495/9333/6310 nM IC50s).

Formula: C₂₄H₃₁N₅O₄S₂

Purity: 99.99%

Color and Shape: Solid

Molecular weight: 517.66

Ref: TM-T36200