CAS 11021-13-9

ginsenoside rb2

Description:

Ginsenoside Rb2 is a natural glycoside and one of the major active components found in ginseng, particularly in Panax ginseng. It belongs to the class of compounds known as saponins, which are characterized by their amphipathic nature, allowing them to interact with both hydrophilic and hydrophobic environments. Ginsenoside Rb2 is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. It is believed to modulate various biological pathways, contributing to its therapeutic potential in conditions such as stress, fatigue, and cognitive decline. The compound typically exhibits low toxicity and is often studied for its role in enhancing immune function and promoting overall health. Its solubility in water is limited, which can affect its bioavailability, making formulation strategies important for its effective use in dietary supplements and herbal medicines. Overall, ginsenoside Rb2 is a significant compound in traditional medicine, with ongoing research exploring its mechanisms of action and potential health benefits.

Formula: C₅₃H₉₀O₂₂

InChI: InChI=1/C53H90O22/c1-23(2)10-9-14-53(8,75-47-43(67)39(63)37(61)29(72-47)22-69-45-41(65)34(58)26(57)21-68-45)24-11-16-52(7)33(24)25(56)18-31-50(5)15-13-32(49(3,4)30(50)12-17-51(31,52)6)73-48-44(40(64)36(60)28(20-55)71-48)74-46-42(66)38(62)35(59)27(19-54)70-46/h10,24-48,54-67H,9,11-22H2,1-8H3/t24-,25+,26-,27+,28+,29+,30-,31+,32-,33-,34-,35+,36+,37+,38-,39?,40-,41+,42+,43+,44+,45-,46-,47-,48-,50-,51+,52+,53-/m0/s1

InChI key: InChIKey=NODILNFGTFIURN-GZPRDHCNSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O)[C@@H](O)CO5)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC6)[H])[H])[H]

Synonyms:

• (3beta,12beta)-12-hydroxy-20-[(6-O-pentopyranosylhexopyranosyl)oxy]dammar-24-en-3-yl 2-O-hexopyranosylhexopyranoside
• (3beta,12beta)-20-{[(3xi)-6-O-(alpha-L-arabinopyranosyl)-beta-D-ribo-hexopyranosyl]oxy}-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• (3β,12β)-20-[(6-O-α-<span class="text-smallcaps">L</smallcap>-Arabinopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</span>-glucopyranoside
• 12-hydroxy-20-[(6-O-pentopyranosylhexopyranosyl)oxy]dammar-24-en-3-yl 2-O-hexopyranosylhexopyranoside
• 20-((6-O-alpha-L-Arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12beta-hydroxydammar-24-en-3beta-yl 2-O-beta-D-glucopyranosyl-beta-D-glucopyranoside
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside C
• Ginsenoside Rb₂
• Nsc 308878
• beta-D-Glucopyranoside, (3-beta,12-beta)-20-((6-O-alpha-L-arabinopyranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl 2-O-beta-D-glucopyranosyl-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-20-[(6-O-α-<smallcap>L</smallcap>-arabinopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-<smallcap>D</span>-glucopyranosyl-
• Ginsenoside Rb2
• (3β,12β)-20-[(6-O-α-L-Arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
• Dammarane, β-D-glucopyranoside deriv.
• β-D-Glucopyranoside, (3β,12β)-20-[(6-O-α-L-arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
• beta-d-glucopyranoside,(3-beta,12-beta)-20-((6-o-alpha-l-arabinopyranosyl-beta
• ginsenosidec
• -d-glucopyranosyl)oxy)-12-hydroxydammar-24-en-3-yl2-o-beta-d-glucopyranosyl-
• arabinopyranosyl-β-D-glucopyranosyl)oxy]-12-
• β-D-Glucopyranoside,(3β,12β)-20-[(6-O-α-L-
• GINSENOSIDE RB2 WITH HPLC

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₅₃H₉₀O₂₂

Purity: (HPLC) ≥97%

Color and Shape: Powder

Molecular weight: 1079.29

Ref: 11-0104S

Ginsenoside Rb2

CAS: 11021-13-9

Formula: C₅₃H₉₀O₂₂

Color and Shape: White To Off-White Solid

Molecular weight: 1079.28

Ref: 4Z-G-157011

Ginsenoside Rb2

CAS: 11021-13-9

Formula: C₅₃H₉₀O₂₂

Molecular weight: 1079.27

Ref: 7W-GC5019

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenosides, which are active compounds found in ginseng (Panax ginseng), are used as antidiabetic treatments; ginsenoside Rb2 may inhibit palmitate-induced gluconeogenesis via AMPK-induced SHP by relieving ER stress, a cause of gluconeogenesis.

Formula: C₅₃H₉₀O₂₂

Purity: 95%~99%

Color and Shape: White powder

Molecular weight: 1079.28

Ref: BP-BP0658

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 (Ginsenoside C) found in species of Panax, upregulating GPR120 gene expression.

Formula: C₅₃H₉₀O₂₂

Purity: 99.01% - 99.93%

Color and Shape: White Powder

Molecular weight: 1079.27

Ref: TM-T3919

Ginsenoside rb2

CAS: 11021-13-9

Natural glycoside

Formula: C₅₃H₉₀O₂₂

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 1079.29

Ref: 5G-89209

Ginsenoside Rb2

Controlled Product

CAS: 11021-13-9

Applications Ginsenoside Rb2 inhibits the catecholamines secretory responses activated by nicotinic stimulation and by direct membrane depolarization from isolated perfused rat adrenal medulla.
References Lim, H., et. al.: Korean J. Physiol. Pha., 18, 431 (2014)

Formula: C₅₃H₉₀O₂₂

Color and Shape: Neat

Molecular weight: 1079.27

Ref: TR-G387605

Ginsenoside Rb2

CAS: 11021-13-9

Ginsenoside Rb2 is a bioactive compound, which is a type of ginsenoside found predominantly in Panax ginseng. It is sourced from the root of the ginseng plant, where it functions as one of the major active constituents contributing to the plant's medicinal properties. The mode of action of Ginsenoside Rb2 involves modulation of multiple signaling pathways, including antioxidant, anti-inflammatory, and anti-cancer pathways. It influences cellular metabolism, apoptosis, and immune responses, thereby playing a critical role in the therapeutic effects of ginseng.

Formula: C₅₃H₉₀O₂₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 1,079.3 g/mol

Ref: 3D-OG09287

Ginsenoside Rb2

CAS: 11021-13-9

Formula: C₅₃H₉₀O₂₂

Molecular weight: 1079.3

Ref: ST-EA-CP-G62002