CAS 110221-44-8: Temocapril hydrochloride
Description:Temocapril hydrochloride is an angiotensin-converting enzyme (ACE) inhibitor primarily used in the treatment of hypertension and heart failure. It is characterized by its ability to inhibit the conversion of angiotensin I to angiotensin II, leading to vasodilation and reduced blood pressure. The compound is typically presented as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate stability profile. Its molecular structure includes a carboxyl group, which is essential for its pharmacological activity. Temocapril hydrochloride is often administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include dizziness, cough, and elevated potassium levels, similar to other ACE inhibitors. As with any medication, it is important for patients to be monitored for potential adverse effects and interactions with other drugs. Overall, Temocapril hydrochloride represents a valuable option in the management of cardiovascular conditions.
Formula:C23H28N2O5S2·ClH
InChI:InChI=1S/C23H28N2O5S2.ClH/c1-2-30-23(29)17(11-10-16-7-4-3-5-8-16)24-18-15-32-20(19-9-6-12-31-19)13-25(22(18)28)14-21(26)27;/h3-9,12,17-18,20,24H,2,10-11,13-15H2,1H3,(H,26,27);1H/t17-,18-,20-;/m0./s1
InChI key:InChIKey=XDDQNOKKZKHBIX-ASBZXGSUSA-N
SMILES:Cl.O=C(O)CN1C(=O)C(NC(C(=O)OCC)CCC=2C=CC=CC2)CSC(C=3SC=CC3)C1
- Synonyms:
- (2S,6R)-6-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid Hydrochloride
- 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, hydrochloride (1:1), (2S,6R)-
- 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)-
- 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, (2S,6R)- (9CI)
- 1,4-Thiazepine-4(5H)-acetic acid, 6-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, monohydrochloride, [2S-[2α,6β(R*)]]-
- Acecol
- Cs-622
- Temocapril Hcl
- TemocarpileHCL
- Temocarpilhydrochloride
- See more synonyms
- [(2S)-6-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl]acetic acid hydrochloride (1:1)
- [(2S,6R)-6-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl]acetic acid
- [(2S,6R)-6-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-5-oxo-2-(thiophen-2-yl)-1,4-thiazepan-4-yl]acetic acid hydrochloride (1:1)
- Temocapril hydrochloride
