CAS 11027-63-7

Agnuside

Description:

Agnuside, with the CAS number 11027-63-7, is a glycoside compound primarily derived from the plant Vitex agnus-castus, commonly known as chaste tree. It is characterized by its chemical structure, which includes a glucose moiety linked to an aglycone, specifically an iridoid compound. Agnuside is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and hormone-regulating effects, particularly in relation to reproductive health. It has been studied for its possible benefits in alleviating symptoms associated with premenstrual syndrome (PMS) and other menstrual disorders. The compound is typically extracted from the fruits or leaves of the chaste tree and is often used in herbal medicine formulations. In terms of solubility, agnuside is generally soluble in water and organic solvents, which facilitates its extraction and incorporation into various therapeutic preparations. Its safety profile and efficacy are subjects of ongoing research, highlighting the importance of understanding its biochemical interactions and potential therapeutic applications.

Formula: C₂₂H₂₆O₁₁

InChI: InChI=1/C22H26O11/c23-8-15-17(26)18(27)19(28)22(32-15)33-21-16-11(7-14(25)13(16)5-6-30-21)9-31-20(29)10-1-3-12(24)4-2-10/h1-7,13-19,21-28H,8-9H2/t13-,14+,15+,16+,17+,18-,19+,21-,22-/m0/s1

InChI key: InChIKey=GLACGTLACKLUJX-QNAXTHAFSA-N

SMILES: O([C@H]1[C@]2([C@]([C@H](O)C=C2COC(=O)C3=CC=C(O)C=C3)(C=CO1)[H])[H])[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O

Synonyms:

• (-)-Buddlejoside A
• (1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl β-<span class="text-smallcaps">D</span>-glucopyranoside
• Agnoside
• Agnuside WITH HPLC
• Agnuside(P)
• Chasteberry Oil
• [(1R,2S,6S,7S)-7-Hydroxy-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3-oxabicyclo[4.3.0]nona-4,8-dien-9-yl]methyl 4-hydroxybenzoate
• [(1S,4aR,5S,7aS)-1-(beta-D-glucopyranosyloxy)-5-hydroxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl, (1α,4aα,5α,7aα)-
• (1S,4aR,5S,7aS)-1,4a,5,7a-Tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl β-D-glucopyranoside
• β-D-Glucopyranoside, 1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl, (1α,4aα,5α,7aα)-
• Agnuside
• β-D-Glucopyranoside, (1S,4aR,5S,7aS)-1,4a,5,7a-tetrahydro-5-hydroxy-7-[[(4-hydroxybenzoyl)oxy]methyl]cyclopenta[c]pyran-1-yl
• Beta-Caryophyllene CAS 87-44-5
• [(1S,4aR,5S,7aS)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• Agnuside Q: What is the storage condition of
• Agnusid
• Agnuside USP/EP/BP
• OLEUMVITICISNEGUNDO Oil
• Vitex negundo oil，Agnuside
• Agnuside Q: What is the CAS Number of
• Vitex Oil
• Agnuside chasteberry oil
• Agnuside Q: What are the applications of
• AgnusideQ: What is
• [(1R,4aS,5R,7aR)-5-hydroxy-1-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl]methyl 4-hydroxybenzoate
• Agnuside (25 mg)

Agnuside

CAS: 11027-63-7

Other glycosides, natural or reproduced by synthesis, and their salts, ethers, esters and other derivatives

Formula: C₂₂H₂₆O₁₁

Color and Shape: Off-White Powder

Molecular weight: 466.14751

Ref: 45-1012203

Agnuside

CAS: 11027-63-7

Agnuside

Formula: C₂₂H₂₆O₁₁

Purity: ≥98%

Molecular weight: 466.44

Ref: 54-BUP02902

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 466.4352

Ref: IN-DA008R0N

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Molecular weight: 466.44

Ref: 7W-GC8652

Agnuside

CAS: 11027-63-7

Agnuside has anti-arthritic activity, it also shows inhibition of vascular permeability and leukocyte migration in vivo.It inhibited an array of pro-inflammatory mediators (PGE(2) and LTB(4)) and T-cell-mediated cytokines (IL-2, TNF-α, IFN-γ, IL-4, IL-10, IL-17).

Formula: C₂₂H₂₆O₁₁

Purity: 95%~99%

Molecular weight: 466.439

Ref: BP-BP0125

Agnuside (Standard)

CAS: 11027-63-7

Agnuside (Standard) is a reference standard for research and analysis in studies involving Agnuside. Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration. It also inhibits 46.3, 66.8, and 82.1% of P-glycoprotein (P-gp) ATPase activity at concentrations of 5, 25, and 100 μM, respectively.

Formula: C₂₂H₂₆O₁₁

Color and Shape: Solid

Molecular weight: 466.44

Ref: TM-TMSM-2837

Agnuside

CAS: 11027-63-7

Agnuside analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₂₆O₁₁

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 466.44

Ref: 11-0235S

Agnuside

CAS: 11027-63-7

Agnuside (chasteberry oil) inhibits COX-2 (IC50: 0.026 mg/ml) but exhibits less than 10% inhibition of COX-1 at this concentration.

Formula: C₂₂H₂₆O₁₁

Purity: 99.08% - 99.81%

Color and Shape: Orangish-Yellow To Light Yellow Liquid

Molecular weight: 466.44

Ref: TM-T3868

Agnuside

CAS: 11027-63-7

((1S,4aR,5S,7aS)-5-Hydroxy-1-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-1,4a,5,7a-tetrahydrocyclopenta[c]pyran-7-yl)methyl 4-hydroxybenzoate

Formula: C₂₂H₂₆O₁₁

Purity: 98%

Molecular weight: 466.44

Ref: IN-DG112831

Agnuside

CAS: 11027-63-7

Natural glycoside

Formula: C₂₂H₂₆O₁₁

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 466.44

Ref: 5G-89155

Agnuside

Controlled Product

CAS: 11027-63-7

Applications Agnuside is an known iridoid glycoside found in Vitex herbs or plants. Agnuside have been used in various applications including in the treatment of premenstrual syndrome and regulation of menopause symptoms. This is mainly due to the fact that Agnuside exhibits estrogen-like activities as it interacts with estrogen receptors (ER-alpha) and estrogen receptor-regulated pregesterone receptors. Recent studies have also evaluated Agnuside for the probable mechanism of anti-arthritic activity, which suggested the possible development of Agnuside as a therapeutic agent in the treatment of arthritis by the modulation of the host immune response.
References Pandey, A., et al.: Inflamm. Rsch., 61, 293 (2012); Leitao, S.G., et al.: Revista. Brasileira. Farmacognosia., 21, 874 (2011); Hu, Y., et al.: J. Pharma. Pharmacol., 59, 1307 (2007);

Formula: C₂₂H₂₆O₁₁

Color and Shape: Neat

Molecular weight: 466.44

Ref: TR-A427020

Agnuside

CAS: 11027-63-7

Agnuside is a diterpenoid compound, which is a phytoconstituent primarily sourced from the plant Vitex agnus-castus, commonly known as chaste tree. This compound is extracted from the fruit of the plant through a series of isolation and purification processes aimed at preserving its chemical integrity.

Formula: C₂₂H₂₆O₁₁

Purity: Min. 95 Area-%

Color and Shape: Brown Powder

Molecular weight: 466.44 g/mol

Ref: 3D-MA08289

Agnuside

CAS: 11027-63-7

Purity: 98%

Molecular weight: 466.4389954

Ref: 10-F866383

Agnuside

CAS: 11027-63-7

Formula: C₂₂H₂₆O₁₁

Molecular weight: 466.44

Ref: ST-EA-CP-A176000