1,3-Propanediol, 2-(phenylmethyl)-, 1-acetate, (2R)-, also known by its CAS number 110270-49-0, is an organic compound characterized by its ester functional group, which is derived from the reaction of 1,3-propanediol and phenylmethyl acetate. This compound features a chiral center, indicating that it exists in two enantiomeric forms, with the (2R) configuration being one of them. It is typically a colorless to pale yellow liquid with a pleasant odor, and it is soluble in organic solvents. The presence of both hydroxyl and acetate groups contributes to its reactivity, making it useful in various chemical syntheses and applications, including as a potential intermediate in the production of pharmaceuticals and fragrances. Additionally, its structural characteristics may impart specific biological activities, which can be of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with any chemical substance.

1,3-Propanediol, 2-(phenylMethyl)-, 1-acetate, (2R)-

110270-49-0: 1,3-Propanediol, 2-(phenylmethyl)-, 1-acetate, (2R)-, also known by its CAS number 110270-49-0, is an organic compound characterized by its ester functional group, which is derived from the reaction of 1,3-propanediol and phenylmethyl acetate. This compound features a chiral center, indicating that it exists in two enantiomeric forms, with the (2R) configuration being one of them. It is typically a colorless to pale yellow liquid with a pleasant odor, and it is soluble in organic solvents. The presence of both hydroxyl and acetate groups contributes to its reactivity, making it useful in various chemical syntheses and applications, including as a potential intermediate in the production of pharmaceuticals and fragrances. Additionally, its structural characteristics may impart specific biological activities, which can be of interest in medicinal chemistry. Safety data should be consulted for handling and storage, as with any chemical substance.

<p>Applications (R)-2-Benzyl-3-hydroxypropyl Acetate is an intermediate in the synthesis of Retorphan (R278500), a powerful and selective inhibitors of neprilysin and are being developed as therapeutic agents. Retorphan behave as the prodrug of the enantiomers of Thiorphan (T369500).<br>References Monteil, T., et al.: Synth. Commun., 31, 211 (2001);<br></p>

CAS 110270-49-0

1,3-Propanediol, 2-(phenylMethyl)-, 1-acetate, (2R)-

(R)-2-Benzyl-3-hydroxypropyl Acetate

Ref: TR-B278830