
CAS 110314-48-2
:Adozelesin
Description:
Adozelesin, with the CAS number 110314-48-2, is a synthetic compound that belongs to the class of antitumor agents. It is a member of the alkylating agents, which function by interfering with DNA replication and transcription, ultimately leading to cell death, particularly in rapidly dividing cancer cells. Adozelesin is characterized by its ability to form covalent bonds with DNA, resulting in cross-linking that disrupts the normal function of the genetic material. This mechanism of action makes it a candidate for use in cancer chemotherapy. The compound is typically administered in a clinical setting and has been studied for its efficacy against various types of tumors. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for determining its therapeutic potential and safety profile. As with many chemotherapeutic agents, the use of Adozelesin may be associated with side effects, necessitating careful monitoring during treatment. Overall, Adozelesin represents a significant area of research in the development of targeted cancer therapies.
Formula:C30H22N4O4
InChI:InChI=1S/C30H22N4O4/c1-15-13-31-27-22(35)11-25-30(26(15)27)12-18(30)14-34(25)29(37)21-9-17-8-19(6-7-20(17)33-21)32-28(36)24-10-16-4-2-3-5-23(16)38-24/h2-11,13,18,31,33H,12,14H2,1H3,(H,32,36)
InChI key:InChIKey=BYRVKDUQDLJUBX-UHFFFAOYSA-N
SMILES:C(=O)(N1C=2C3(C(C3)C1)C4=C(C(=O)C2)NC=C4C)C5=CC=6C(N5)=CC=C(NC(=O)C7=CC=8C(O7)=CC=CC8)C6
Synonyms:- 2-Benzofurancarboxamide, N-[2-[[(7bR,8aS)-4,5,8,8a-tetrahydro-7-methyl-4-oxocyclopropa[c]pyrrolo[3,2-e]indol-2(1H)-yl]carbonyl]-1H-indol-5-yl]-
- N-[2-[[(7bR,8aS)-4,5,8,8a-Tetrahydro-7-methyl-4-oxocyclopropa[c]pyrrolo[3,2-e]indol-2(1H)-yl]carbonyl]-1H-indol-5-yl]-2-benzofurancarboxamide
- 2-Benzofurancarboxamide, N-[2-[(4,5,8,8a-tetrahydro-7-methyl-4-oxocyclopropa[c]pyrrolo[3,2-e]indol-2(1H)-yl)carbonyl]-1H-indol-5-yl]-, (7bR)-
- Cyclopropa[c]benzo[1,2-b:4,3-b′]dipyrrole, 2-benzofurancarboxamide deriv.
- U 73975
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Adolezesin
CAS:https://pubmed.ncbi.nlm.nih.gov/1624543/Formula:C30H22N4O4Color and Shape:SolidMolecular weight:502.52
