CAS 11032-98-7

Desmycosin

Description:

Desmycosin, with the CAS number 11032-98-7, is a chemical compound that belongs to the class of macrolide antibiotics. It is derived from the fermentation of certain Streptomyces species. Desmycosin exhibits antibacterial properties, primarily targeting Gram-positive bacteria, and is known for its effectiveness against various infections. The compound features a complex molecular structure characterized by a large lactone ring, which is typical of macrolides, contributing to its biological activity. Desmycosin's mechanism of action involves inhibiting bacterial protein synthesis by binding to the 50S ribosomal subunit, thereby preventing the growth and reproduction of bacteria. In terms of physical properties, it is typically a solid at room temperature and may exhibit solubility in organic solvents. As with many antibiotics, the use of desmycosin is subject to considerations regarding resistance development, necessitating careful application in clinical settings. Overall, desmycosin represents an important compound in the field of medicinal chemistry, particularly in the development of antimicrobial therapies.

Formula: C₃₉H₆₅NO₁₄

InChI: InChI=1/C39H65NO14/c1-11-29-26(19-50-39-37(49-10)36(48-9)33(46)24(6)52-39)16-20(2)12-13-27(42)21(3)17-25(14-15-41)35(22(4)28(43)18-30(44)53-29)54-38-34(47)31(40(7)8)32(45)23(5)51-38/h12-13,15-16,21-26,28-29,31-39,43,45-47H,11,14,17-19H2,1-10H3/b13-12+,20-16+/t21-,22+,23-,24-,25+,26-,28-,29-,31+,32-,33-,34-,35-,36-,37-,38+,39-/m1/s1

InChI key: InChIKey=QRPHLEPFYLNRDA-NLGRAQRVSA-N

SMILES: O([C@H]1[C@@H](CC=O)C[C@@H](C)C(=O)/C=C/C(/C)=C/[C@H](CO[C@H]2[C@H](OC)[C@H](OC)[C@H](O)[C@@H](C)O2)[C@@H](CC)OC(=O)C[C@@H](O)[C@@H]1C)[C@H]3[C@H](O)[C@@H](N(C)C)[C@H](O)[C@@H](C)O3

Synonyms:

• 4^A-O-De(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)tylosin
• Demycarosyltylosin
• Desmycosin
• Oxacyclohexadecane, tylosin deriv.
• Tylosin, 4^A-O-de(2,6-dideoxy-3-C-methyl-α-<span class="text-smallcaps">L</span>-ribo-hexopyranosyl)-
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-alpha-L-ribo-hexopyranosyl)-
• [(2R,3R,4E,6E,9R,11R,12S,13S,14R)-12-{[3,6-dideoxy-3-(dimethylamino)-β-D-glucopyranosyl]oxy}-2-ethyl-14-hydroxy-5,9,13-trimethyl-8,16-dioxo-11-(2-oxoethyl)oxacyclohexadeca-4,6-dien-3-yl]methyl 6-deoxy-2,3-di-O-methyl-β-D-allopyranoside
• Tylosin B
• Tylosin, 4A-O-de(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)-
• 4A-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tylosin
• Tylosin BQ: What is
• Tylosin B Q: What is the storage condition of
• Tylosin B Q: What is the CAS Number of
• 2-((4R,5S,6S,7R,9R,11E,13E,15R,16R)-6-(((2R,3R,4S,5S,6R)-4-(dimethylamino)-3,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-16-ethyl-4-hydroxy-15-((((2R,3R,4R,5R,6R)-5-hydroxy-3,4-dimethoxy-6-methy
• 5-O-De[4-O-(3-C-methyl-2,6-dideoxy-α-L-ribo-hexopyranosyl)-3-(dimethylamino)-3,6-dideoxy-β-D-glucopyranosyl]-5-O-[3-(dimethylamino)-3,6-dideoxy-β-D-glucopyranosyl]tyrosine [antibiotic]
• 4'-O-De(2,6-dideoxy-3-C-methyl-α-L-ribo-hexopyranosyl)tyrosine [antibiotic]

Desmycosin

CAS: 11032-98-7

Formula: C₃₉H₆₅NO₁₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 771.9317

Ref: IN-DA008WMO

Tylosin B (Desmycosin)

CAS: 11032-98-7

Formula: C₃₉H₆₅NO₁₄

Color and Shape: Neat

Molecular weight: 771.93

Ref: 04-C17895620

Tylosin B (Desmycosin) 100 µg/mL in Acetonitrile

CAS: 11032-98-7

Formula: C₃₉H₆₅NO₁₄

Color and Shape: Single Solution

Molecular weight: 771.93

Ref: 04-A17895620AL-100

Tylosin B (Desmycosin)

CAS: 11032-98-7

Formula: C₃₉H₆₅NO₁₄

Molecular weight: 771.94

Ref: 4Z-T-175009

Desmycosin

Controlled Product

CAS: 11032-98-7

Applications Desmycosin is a 16-membered macrolide antibiotic and a metabolite of Tylosin (T947650). Desmycosin is also a precursor to Tilmicosin (T440500).
References Wal, J.M. et al.: J. Antibiot., 26, 687 (1973); Hu, D. et al.: Environ. Toxicol. Chem., 26, 884 (2007); Min, Y. et al.: Proc. Biochem., 42, 729 (2007);

Formula: C₃₉H₆₅NO₁₄

Color and Shape: White To Light Beige

Molecular weight: 771.93

Ref: TR-D296870