CAS 110390-84-6

Perbufylline

Description:

Perbufylline is a chemical compound that belongs to the class of xanthine derivatives, which are known for their pharmacological properties, particularly as bronchodilators. It is characterized by its ability to inhibit phosphodiesterase, leading to increased levels of cyclic AMP in cells, which can result in smooth muscle relaxation and anti-inflammatory effects. Perbufylline has been studied for its potential therapeutic applications in respiratory diseases, such as asthma and chronic obstructive pulmonary disease (COPD). The compound is typically administered in a pharmaceutical form, and its efficacy and safety profile have been evaluated in various clinical settings. As with many xanthine derivatives, it may exhibit side effects related to its stimulant properties, including cardiovascular effects and gastrointestinal disturbances. The compound's chemical structure contributes to its biological activity, and ongoing research may further elucidate its mechanisms of action and potential uses in medicine.

Formula: C₂₃H₂₈FN₅O₃

InChI: InChI=1/C23H28FN5O3/c1-26-21-19(22(31)27(2)23(26)32)29(15-25-21)12-4-3-11-28-13-9-17(10-14-28)20(30)16-5-7-18(24)8-6-16/h5-8,15,17H,3-4,9-14H2,1-2H3

SMILES: Cn1c2c(c(=O)n(C)c1=O)n(CCCCN1CCC(CC1)C(=O)c1ccc(cc1)F)cn2

Synonyms:

• Perbufylline [INN]
• 7-(4-(4-(p-Fluorobenzoyl)piperidino)butyl)theophylline
• Unii-M69H5Tdq1K
• 7-(4-{4-[(4-fluorophenyl)carbonyl]piperidin-1-yl}butyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione

7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione

Controlled Product

CAS: 110390-84-6

7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione is a drug that belongs to the group of adenosine receptor antagonists. It has been shown to inhibit phosphodiesterase activity and is used as a pharmaceutical dosage. 7-[4-[4-(4-Fluorobenzoyl)Piperidin-1-Yl]Butyl]-1,3-Dimethylpurine-2,6-Dione has been shown to bind to the 5HT2C receptor in vitro. This drug may have therapeutic potential for obesity and type 2 diabetes mellitus treatment.

Formula: C₂₃H₂₈FN₅O₃

Purity: Min. 95%

Molecular weight: 441.5 g/mol

Ref: 3D-FF99814

Perbufylline

CAS: 110390-84-6

Perbufylline, a N-methylated xanthine, is a bronchodilator antagonizing 5-HT2 and alpha1-adrenoceptors.

Formula: C₂₃H₂₈FN₅O₃

Color and Shape: Solid

Molecular weight: 441.5

Ref: TM-T71447