CAS 1104-22-9: meclizine dihydrochloride

Description:Meclizine dihydrochloride is an antihistamine primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and vertigo. It is a white to off-white crystalline powder that is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. The compound acts as a selective antagonist of the H1 histamine receptor, which helps to alleviate symptoms by blocking the effects of histamine in the body. Meclizine dihydrochloride has a relatively long duration of action, which contributes to its effectiveness in managing motion sickness. It is typically administered orally and may be available in tablet or chewable form. Common side effects can include drowsiness, dry mouth, and fatigue, which are typical of many antihistamines. Due to its sedative properties, caution is advised when operating machinery or driving after taking the medication. Overall, meclizine dihydrochloride is a valuable therapeutic agent in the management of vestibular disorders and motion-related symptoms.

Formula:C₂₅H₂₇ClN₂·2ClH

InChI:InChI=1S/C25H27ClN2.2ClH/c1-20-6-5-7-21(18-20)19-27-14-16-28(17-15-27)25(22-8-3-2-4-9-22)23-10-12-24(26)13-11-23;;/h2-13,18,25H,14-17,19H2,1H3;2*1H

InChI key:InChIKey=VCTHNOIYJIXQLV-UHFFFAOYSA-N

SMILES:Cl.ClC1=CC=C(C=C1)C(C=2C=CC=CC2)N3CCN(CC=4C=CC=C(C4)C)CC3

Synonyms:
1-(p-Chloro-α-phenylbenzyl)-4-(m-methylbenzyl)piperazine dihydrochloride
1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-(3-Methylbenzyl)Piperazine
1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-(3-Methylbenzyl)Piperazine Dihydrochloride
1-[(4-Chlorophenyl)(Phenyl)Methyl]-4-(3-Methylbenzyl)Piperazine Hydrochloride (1:1)
1-[(4-Chlorophenyl)(phenyl)methyl]-4-[(3-methylphenyl)methyl]piperazine dihydrochloride
Ancolan dihydrochloride
Bonamine
Diadril
Meclizine hcl
Meclizine hydrochloride
See more synonyms
Meclozine Dihydrochloride
Meclozine hydrochloride
NSC 28728
Navidoxine
Parachloramine dihydrochloride
Piperazine, 1-(p-chloro-α-phenylbenzyl)-4-(m-methylbenzyl)-, dihydrochloride
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, dihydrochloride
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-4-[(3-methylphenyl)methyl]-, hydrochloride (1:2)
Postafen
Postafene dihydrochloride
Zentrip
Meclizine dihydrochloride

Found 12 products.

Product data	Purity	Price range	Estimated delivery
Meclozine hydrochloride REF: 47-220CAS: 1104-22-9	- - -	211.00 €	Tue 15 Apr 25
Meclozine dihydrochloride CRS REF: 41-M0220000CAS: 1104-22-9	- - -	115.00 €	Tue 15 Apr 25
Meclizine dihydrochloride REF: TM-T1110CAS: 1104-22-9	98.05% - 99.79%	55.00 €	Thu 17 Apr 25
Meclizine DiHCl REF: 4Z-M-401CAS: 1104-22-9	- - -	To inquire	Mon 21 Apr 25
Meclizine Dihydrochloride REF: 54-OR1030341CAS: 1104-22-9	98%	32.00 €~1,143.00 €	Mon 21 Apr 25
Meclizine dihydrochloride REF: 54-BUP17363CAS: 1104-22-9	98.09%	84.00 €~767.00 €	Mon 21 Apr 25
Meclizine dihydrochloride REF: 7W-GP7447CAS: 1104-22-9	≥ 97.0%	To inquire	Mon 21 Apr 25
Meclozine Dihydrochloride REF: 86-MM0586.00-0250CAS: 1104-22-9	- - -	580.00 €	Tue 22 Apr 25
1-((4-Chlorophenyl)(phenyl)methyl)-4-(3-methylbenzyl)piperazine dihydrochloride REF: 10-F079238CAS: 1104-22-9	95.0%	To inquire	Tue 29 Apr 25
Meclizine Dihydrochloride REF: TR-M202695CAS: 1104-22-9	- - -	102.00 €~143.00 €	Tue 29 Apr 25
Meclizinedihydrochloride REF: 3D-FM156453CAS: 1104-22-9	Min. 98 Area-%	143.00 €~5,195.00 €	Mon 28 Apr 25
Meclizine Dihydrochloride REF: 3B-M2755CAS: 1104-22-9 569-65-3	>98.0%(HPLC)	- - -	Discontinued product