CAS 11041-12-6

Cholestyramine

Description:

Cholestyramine is a bile acid sequestrant primarily used to lower cholesterol levels in patients with hyperlipidemia and to manage certain types of diarrhea. It is a synthetic, insoluble polymer that binds bile acids in the gastrointestinal tract, preventing their reabsorption and promoting their excretion. This mechanism leads to a reduction in circulating cholesterol levels as the liver compensates for the loss of bile acids by converting cholesterol into bile. Cholestyramine is typically administered as a powder that is mixed with water or other liquids before consumption. It is known for its potential side effects, which may include gastrointestinal discomfort, constipation, and interference with the absorption of fat-soluble vitamins and other medications. The substance is not absorbed into the bloodstream, which contributes to its safety profile but also necessitates careful monitoring of nutrient levels in long-term use. Overall, cholestyramine plays a significant role in lipid management and is an important therapeutic option in specific clinical scenarios.

Formula: Unspecified

Synonyms:

• Cholebar
• Cholestyramin
• Cholestyramine
• Cholestyramine Chloride
• Cholestyramine hydroxide
• Cholybar
• Colestiramina
• Colestyramin
• Colestyramine
• Cuemid
• Divistyramine
• Dowex 1-X2-Cl
• LoCholest
• Mk-135
• Quantalan
• Questran
• Questran Light
• Resin, Cholestyramine

Colestyramine

CAS: 11041-12-6

Colestyramine

Color and Shape: White To Light Pink

Ref: 47-551

COLESTYRAMINE CRS

CAS: 11041-12-6

COLESTYRAMINE CRS

Formula: C₂₁H₃₀ClN

Molecular weight: 331.9226

Ref: 41-Y0000374

Cholestyramine Resin

CAS: 11041-12-6

Cross-linked polyvinylbenzyltrimethylammonium chloride (cholestyramine resin usp)

Formula: C₂₁H₃₀ClN

Color and Shape: White Off-White Powder

Molecular weight: 331.92

Ref: 45-1133004

Cholestyramine resin

CAS: 11041-12-6

Formula: C₂₈H₄₈ClN

Color and Shape: Solid

Molecular weight: 434.1404

Ref: IN-DA008RK3

Cholestyramine

CAS: 11041-12-6

Cholestyramine (Cholestyramine resin), a bile acid-binding resin, inhibits intestinal bile acid absorption which results in the increasing bile acid synthesis

Formula: C₂₇H₄₇ClN₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 435.14

Ref: TM-T13622

Cholestyramine

CAS: 11041-12-6

Cholestyramine

Purity: ≥95%

Molecular weight: 435.14g/mol

Ref: 54-BUP17993

Cholestyramine

CAS: 11041-12-6

Cholestyramine

Purity: RG

Ref: 54-BIC0227

Cholestyramine (Technical Grade)

CAS: 11041-12-6

Applications Cholestyramine is used in biological study for current trends in anti-thyroid drug treatment of Graves disease. It is also used in pharmacological activity in treatment of capecitabine-induced enterocolitis.
References Abusneineh, B., et al.: Translational Gastrointestinal Cancer, 4, 252-255 (2015); Okosieme, O. E., & Lazarus, J. H.: Expert Opin. Pharmaco., 17, 2005-2017 (2016);

Formula: (C₂₆H₄₀ClN)n

Color and Shape: White To Light Pink

Molecular weight: 0.00

Ref: TR-C432555

Cholestyramine resin

CAS: 11041-12-6

Cholestyramine is a resin that is used to lower cholesterol levels in the blood. It binds to bile acids, which are produced in the liver from cholesterol, and prevents their reabsorption from the intestines. Cholestyramine resin is used as a dietary supplement for patients with erythropoietic protoporphyria or for those who have had gallstones removed. This drug also reduces serum bile acid concentrations and has been shown to inhibit cholesterol synthesis in animal experiments. Cholestyramine resin has not been shown to affect glomerular filtration rate or renal function in humans. Cholestyramine may interfere with certain laboratory tests, such as blood sampling, because it can bind to proteins and alter their structure.

Formula: C₂₇H₄₇ClN₂

Color and Shape: Powder

Molecular weight: 435.1 g/mol

Ref: 3D-FC178609